Observational studyPathogens (Basel, Switzerland)2026
Tick-Borne Infections: Results from a Prospective Observational Study from a Single Centre in Northern Italy.
Andrea Tedesco, Pietro Sponga, Giulia Bertoli, Andrea Matucci, Graziana Da Rold, Federica Obber, Lucia Moro, Chiara Piubelli, Francesca Perandin, Concetta Castilletti and 5 more
Abstract readObservational Study
In one paragraphObservational study in Pathogens (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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0citing papers in PubMed
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
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4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
15 authors.
Andrea TedescoDepartment of Infectious, Tropical Diseases and Microbiology, IRCCS Sacro Cuore Don Calabria Hospital, Negrar di Valpolicella, 37024 Verona, Italy.ORCID 0000-0001-5097-1890 Pietro SpongaDepartment of Infectious and Tropical Diseases, Careggi University Hospital, 50134 Florence, Italy.
Giulia BertoliDepartment of Infectious, Tropical Diseases and Microbiology, IRCCS Sacro Cuore Don Calabria Hospital, Negrar di Valpolicella, 37024 Verona, Italy.ORCID 0000-0003-4175-1620 Andrea MatucciDepartment of Infectious, Tropical Diseases and Microbiology, IRCCS Sacro Cuore Don Calabria Hospital, Negrar di Valpolicella, 37024 Verona, Italy.ORCID 0000-0001-9368-850X Graziana Da RoldUnit of Ecopathology Wildelife Specialistic Center-SCT2-Belluno, Istituto Zooprofilattico Sperimentale delle Venezie (IZSVe), 32100 Belluno, Italy.ORCID 0000-0002-4935-0349 Federica ObberUnit of Ecopathology Wildelife Specialistic Center-SCT2-Belluno, Istituto Zooprofilattico Sperimentale delle Venezie (IZSVe), 32100 Belluno, Italy.ORCID 0000-0002-5459-7880 Lucia MoroDepartment of Infectious, Tropical Diseases and Microbiology, IRCCS Sacro Cuore Don Calabria Hospital, Negrar di Valpolicella, 37024 Verona, Italy.ORCID 0000-0002-6017-1181 Chiara PiubelliDepartment of Infectious, Tropical Diseases and Microbiology, IRCCS Sacro Cuore Don Calabria Hospital, Negrar di Valpolicella, 37024 Verona, Italy.ORCID 0000-0002-5739-3795 Francesca PerandinDepartment of Infectious, Tropical Diseases and Microbiology, IRCCS Sacro Cuore Don Calabria Hospital, Negrar di Valpolicella, 37024 Verona, Italy.ORCID 0000-0003-3933-3892 Concetta CastillettiDepartment of Infectious, Tropical Diseases and Microbiology, IRCCS Sacro Cuore Don Calabria Hospital, Negrar di Valpolicella, 37024 Verona, Italy.ORCID 0000-0001-9819-236X Fabio FormentiDepartment of Infectious, Tropical Diseases and Microbiology, IRCCS Sacro Cuore Don Calabria Hospital, Negrar di Valpolicella, 37024 Verona, Italy.ORCID 0000-0003-3203-0872 Cristina MazziDepartment of Infectious, Tropical Diseases and Microbiology, IRCCS Sacro Cuore Don Calabria Hospital, Negrar di Valpolicella, 37024 Verona, Italy.ORCID 0000-0002-4561-3447 Salvatore ScarsoDepartment of Infectious, Tropical Diseases and Microbiology, IRCCS Sacro Cuore Don Calabria Hospital, Negrar di Valpolicella, 37024 Verona, Italy.ORCID 0000-0003-2956-8997 Dora BuonfrateDepartment of Infectious, Tropical Diseases and Microbiology, IRCCS Sacro Cuore Don Calabria Hospital, Negrar di Valpolicella, 37024 Verona, Italy.ORCID 0000-0003-0108-6822 Federico GobbiDepartment of Infectious, Tropical Diseases and Microbiology, IRCCS Sacro Cuore Don Calabria Hospital, Negrar di Valpolicella, 37024 Verona, Italy.ORCID 0000-0002-6899-4545 Funding
Ministero della Salute L3P5
6 · The paper itselfAbstract
backgroundData on tick-borne diseases (TBDs) in Italy are fragmented. This study aimed to describe tick-borne pathogens (TBPs) and TBDs observed in a hospital in Italy and to assess the correlation between TBPs and human disease.
methodsA prospective observational study was conducted in a single hospital between March 2024 and January 2025. Inclusion criteria were: individuals ≥ 8 years of age and consent to study participation. Data and blood samples were collected at baseline (T0), and 12-18 weeks later (T1). Ticks collected at T0 were pooled and analyzed by real-time PCR. Serological and molecular tests were used for TBD diagnosis.
resultsNinety-three individuals (median age 39 years; 52.7% female) were enrolled. The pathogens most frequently detected in the tick pools were
conclusionsThe low concordance between pathogens detected in participant-level tick pools and confirmed human tick-borne disease supports the limited clinical value of tick testing in this setting.
Indexed as
Tick-Borne DiseasesAdolescentAdultAgedAnimalsBorreliaChildEncephalitis, Tick-BorneFemaleHumansItalyLyme DiseaseMaleMiddle AgedProspective StudiesRickettsiaborreliosisLyme borreliosisSENLATTBEtick-borne diseasesvector-borne diseases
Identifiers
PMID42515063
PMCPMC13414487
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