Evidence map›Paper›PMID 42515060›Full record

ReviewPathogens (Basel, Switzerland)2026

Host-Microbiome Immune Interaction Networks: A Comparative Evolutionary Perspective Across Worms, Mice, and Humans.

Xuanheng Tai, Yiying Zhang, Huijie Yang, Wei Zou

Abstract readReview
In one paragraph

Review in Pathogens (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xuanheng TaiYunnan Provincial Key Laboratory of Public Health and Biosafety, School of Public Health, Kunming Medical University, Kunming 650500, China.
Yiying ZhangYunnan Provincial Key Laboratory of Public Health and Biosafety, School of Public Health, Kunming Medical University, Kunming 650500, China.ORCID 0009-0007-4268-960X
Huijie YangYunnan Provincial Key Laboratory of Public Health and Biosafety, School of Public Health, Kunming Medical University, Kunming 650500, China.
Wei ZouYunnan Provincial Key Laboratory of Public Health and Biosafety, School of Public Health, Kunming Medical University, Kunming 650500, China.

Funding

National Natural Science Foundation of China No. 32560306
6 · The paper itself

Abstract

The immunological paradigm is undergoing profound shifts. Classic "self-nonself" recognition remains foundational, but microbiome research has expanded immunological models toward homeostasis, tolerance, and host-microbe co-regulation. Within this framework, gut microbiota act as the core drivers of the development and calibration of the host immune system. This review examines host-microbiome immune interactions across species from a macroevolutionary perspective. We use

Indexed as

Biological EvolutionCaenorhabditis elegansGastrointestinal MicrobiomeHost Microbial InteractionsHost-Pathogen InteractionsMicrobiotaAdaptive ImmunityAnimalsHumansImmunity, InnateMiceand precision medicineevolutionary mismatchholobiontimmune homeostasismicrobiome–immune interactionssurveillance immunity

Identifiers

PMID42515060
PMCPMC13415120

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.