Evidence map›Paper›PMID 42514920›Full record

ArticlePharmaceutics2026

Exploiting the T790M Gatekeeper: A Theoretical Blueprint for Non-Covalent Inhibition of in

Shrikant S Nilewar, Shuvadip Khanra, Manav Pandya, Sandesh Lodha, Perli Kranti Kumar, Nagaraju Bandaru, Antonio Jose Naranjo-Redondo, Ricardo Pérez-Pastén-Borja, Tushar Janardan Pawar

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceutics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shrikant S NilewarDepartment of Pharmaceutical Chemistry, Maliba Pharmacy College, Uka Tarsadia University, Bardoli 394350, Gujarat, India.ORCID 0000-0002-5794-9191
Shuvadip KhanraDepartment of Pharmaceutical Chemistry, Maliba Pharmacy College, Uka Tarsadia University, Bardoli 394350, Gujarat, India.ORCID 0009-0007-7782-2909
Manav PandyaDepartment of Pharmaceutical Chemistry, Maliba Pharmacy College, Uka Tarsadia University, Bardoli 394350, Gujarat, India.
Sandesh LodhaDepartment of Pharmaceutical Chemistry, Maliba Pharmacy College, Uka Tarsadia University, Bardoli 394350, Gujarat, India.ORCID 0000-0002-7783-6485
Perli Kranti KumarDepartment of Pharmaceutical Analysis, J.K.K. Nattraja College of Pharmacy, Kumarapalayam 638183, Tamil Nadu, India.ORCID 0009-0004-1202-535X
Nagaraju BandaruDepartment of Pharmacology, Sree Dattha Institute of Pharmacy Sheriguda, Ibrahimpatnam, Hyderabad 501510, Telangana, India.ORCID 0000-0003-2059-4849
Antonio Jose Naranjo-RedondoDivisión de Ingeniería, Universidad Anáhuac Querétaro, Circuito Universidades I, Fracción 2 S/N, Zibatá, El Marqués 76246, Querétaro, Mexico.
Ricardo Pérez-Pastén-BorjaDepartamento de Farmacia, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Unidad Académica Adolfo López Mateos, Del. GAM, Mexico City 77380, Mexico.
Tushar Janardan PawarDivisión de Ingeniería, Universidad Anáhuac Querétaro, Circuito Universidades I, Fracción 2 S/N, Zibatá, El Marqués 76246, Querétaro, Mexico.ORCID 0000-0003-0753-9538

Funding

Universidad Anáhuac Querétaro
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

drug resistanceEGFR T790Mfree energy landscapegenerative artificial intelligencemolecular dynamicsnon-covalent inhibitorssulfur anchoring

Identifiers

PMID42514920
PMCPMC13416115

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.