Evidence map›Paper›PMID 42514907›Full record

ArticlePharmaceutics2026

Preclinical Pharmacokinetics of a Triple-Combination Intravaginal Ring for HIV Prevention.

John A Moss, Priya Srinivasan, Irina Butkyavichene, Manjula Gunawardana, Amalia E Castonguay, John M Cortez, Patricia Galvan, Sofia Rivera, Jining Zhang, Chuong Dinh and 9 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceutics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

John A MossDepartment of Chemistry, Oak Crest Institute of Science, Monrovia, CA 91016, USA.ORCID 0000-0001-8091-3245
Priya SrinivasanLaboratory Branch, Division of HIV Prevention, National Center for HIV, Viral Hepatitis, Sexually Transmitted Diseases, and Tuberculosis Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA.
Irina ButkyavicheneDepartment of Chemistry, Oak Crest Institute of Science, Monrovia, CA 91016, USA.
Manjula GunawardanaDepartment of Chemistry, Oak Crest Institute of Science, Monrovia, CA 91016, USA.ORCID 0000-0002-3137-8669
Amalia E CastonguayDepartment of Chemistry, Oak Crest Institute of Science, Monrovia, CA 91016, USA.ORCID 0000-0002-6358-1784
John M CortezDepartment of Chemistry, Oak Crest Institute of Science, Monrovia, CA 91016, USA.
Patricia GalvanDepartment of Chemistry, Oak Crest Institute of Science, Monrovia, CA 91016, USA.
Sofia RiveraDepartment of Chemistry, Oak Crest Institute of Science, Monrovia, CA 91016, USA.
Jining ZhangLaboratory Branch, Division of HIV Prevention, National Center for HIV, Viral Hepatitis, Sexually Transmitted Diseases, and Tuberculosis Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA.
Chuong DinhLaboratory Branch, Division of HIV Prevention, National Center for HIV, Viral Hepatitis, Sexually Transmitted Diseases, and Tuberculosis Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA.ORCID 0000-0002-1749-4401
Angela HolderLaboratory Branch, Division of HIV Prevention, National Center for HIV, Viral Hepatitis, Sexually Transmitted Diseases, and Tuberculosis Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA.
Dawn LittleKatmai Government Services, Anchorage, AK 99515, USA.ORCID 0000-0002-8066-8988
Shanon BachmanLibra Management Group, Decatur, GA 30030, USA.ORCID 0009-0000-5999-8774
Kristen KelleyThe DESA Group, Columbia, SC 29223, USA.ORCID 0000-0002-4307-3301
Christina M RamirezDepartment of Biostatistics, UCLA Fielding School of Public Health, University of California, Los Angeles (UCLA), Los Angeles, CA 90095, USA.
Philippe A GallayDepartment of Immunology and Microbiology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
Kathleen L VincentDepartment of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, TX 77555, USA.
James M SmithLaboratory Branch, Division of HIV Prevention, National Center for HIV, Viral Hepatitis, Sexually Transmitted Diseases, and Tuberculosis Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA.
Marc M BaumDepartment of Chemistry, Oak Crest Institute of Science, Monrovia, CA 91016, USA.

Funding

Systematic Development of Antiretroviral Intravaginal Rings for HIV PreventionU19AI113048 · NIAID · OAK CREST INSTITUTE OF SCIENCE · PI BAUM, MARC MICHAEL · 2014 to 2018
$18.4M
National Institute of Allergy and Infectious Diseases U19AI113048NIAID NIH HHS U19 AI113048
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

antiretroviral drug deliveryHIV preventionintravaginal ringsvaginal drug delivery

Identifiers

PMID42514907
PMCPMC13415328

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.