Evidence map›Paper›PMID 42514806›Full record

ArticlePolymers2026

Material Properties of Human Bone-Derived Gelatin.

Nikolay A Ryabov, Larisa T Volova, Olga A Karyakina, Sergei S Ivanov, Violetta V Boltovskaya, Denis G Alekseev, Artem D Volov

Abstract read
In one paragraph

Article in Polymers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nikolay A RyabovBioTech Research Institute, Samara State Medical University, Samara 443079, Russia.ORCID 0000-0002-1332-953X
Larisa T VolovaBioTech Research Institute, Samara State Medical University, Samara 443079, Russia.ORCID 0000-0002-8510-3118
Olga A KaryakinaBioTech Research Institute, Samara State Medical University, Samara 443079, Russia.ORCID 0009-0007-6061-7052
Sergei S IvanovBioTech Research Institute, Samara State Medical University, Samara 443079, Russia.ORCID 0009-0003-5850-1887
Violetta V BoltovskayaBioTech Research Institute, Samara State Medical University, Samara 443079, Russia.ORCID 0000-0003-3457-8524
Denis G AlekseevBioTech Research Institute, Samara State Medical University, Samara 443079, Russia.ORCID 0000-0003-4185-0709
Artem D VolovBioTech Research Institute, Samara State Medical University, Samara 443079, Russia.ORCID 0009-0008-2278-7605

Funding

Ministry of Health of the Russian Federation Priority-2030
6 · The paper itself

Abstract

A comprehensive evaluation of allogeneic human bone-derived gelatin (hBG) was conducted as a promising material for regenerative medicine and 3D bioprinting. Comparative analysis with a commercial animal-derived gelatin product (hereinafter CDH) revealed a similar FTIR spectral profile, confirming the retention of key functional groups. Rheological analysis under steady shear showed that hBG is a pseudoplastic fluid with a concentration-dependent viscosity. However, a complete characterization of bioinks requires oscillatory measurements (G', G″, and gelation point), which are planned in future studies. In vitro experiments on spheroid models (chondroblasts) demonstrated biocompatibility, an absence of cytotoxicity, and support for cell viability in 5% and 10% (hBG-5/10) matrices. Owing to its origin, the material allows for the modeling of "human-in-human" conditions, which makes it a promising precursor for the development of bioinks and matrices in regenerative medicine and tissue engineering. However, definitive positioning of the material as a bioink requires additional oscillatory rheological studies (determination of G', G″, thixotropy, and gelation point), which were not performed in the present work.

Indexed as

3D bioprintingallogeneic gelatinbiocompatibilitychondroblastshuman bone tissuespheroidstissue engineering

Identifiers

PMID42514806
PMCPMC13431316

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.