Evidence map›Paper›PMID 42514677›Full record

ArticleVeterinary sciences2026

Association Between Antimicrobial Susceptibility Test Results and Bacteriological Cure of Mild and Moderate Bovine Clinical Mastitis.

Breno Luis Nery Garcia, Carlos Eduardo Fidelis, Kristian da Silva Barbosa, Gustavo Freu, Marcos Veiga Dos Santos

Abstract read
In one paragraph

Article in Veterinary sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Breno Luis Nery GarciaFaculty of Veterinary Medicine, University of Calgary, Calgary, AB T2N 1N4, Canada.ORCID 0000-0003-0188-5595
Carlos Eduardo FidelisDepartment of Animal Nutrition and Production, School of Veterinary Medicine and Animal Science, University of São Paulo, Pirassununga 13635-900, São Paulo, Brazil.ORCID 0000-0003-4205-1423
Kristian da Silva BarbosaDepartment of Animal Nutrition and Production, School of Veterinary Medicine and Animal Science, University of São Paulo, Pirassununga 13635-900, São Paulo, Brazil.ORCID 0009-0002-7318-1407
Gustavo FreuDepartment of Animal Nutrition and Production, School of Veterinary Medicine and Animal Science, University of São Paulo, Pirassununga 13635-900, São Paulo, Brazil.ORCID 0000-0003-2708-5414
Marcos Veiga Dos SantosDepartment of Animal Nutrition and Production, School of Veterinary Medicine and Animal Science, University of São Paulo, Pirassununga 13635-900, São Paulo, Brazil.ORCID 0000-0002-4273-3494

Funding

Fundação de Amparo à Pesquisa do Estado de São Paulo 2021/05400-3Fundação de Amparo à Pesquisa do Estado de São Paulo 2021/09134-6
6 · The paper itself

Abstract

Antimicrobial resistance (AMR) is a global concern partly driven by excessive antimicrobial use (AMU) in animal production. Clinical mastitis (CM) is a leading cause of AMU in dairy farms, highlighting its importance from a public-health perspective. This observational study aimed to evaluate the use of antimicrobial susceptibility testing as a criterion for selecting antimicrobials for the treatment of mild and moderate CM in dairy cows. To this end, the association between in vitro antimicrobial susceptibility test results of mastitis-causing pathogens and in vivo bacteriological cure (BC) was assessed. A total of 340 cows with mild or moderate CM from 14 commercial dairy herds in Brazil were enrolled in the study. Isolates from the pretreatment milk samples were subjected to antimicrobial susceptibility testing (AST) using agar disk diffusion. Susceptibility results and cow-level variables were included in a generalized linear mixed model (GLMM) to evaluate their association with BC. No significant association was found between the antimicrobial susceptibility results and BC of the mastitis cases. In conclusion, although in vitro susceptibility testing remains an important tool for AMR surveillance, the findings of this study suggest that its utility in guiding antimicrobial treatment decisions in CM cases is limited.

Indexed as

antimicrobial resistanceantimicrobial susceptibility testingmastitis

Identifiers

PMID42514677
PMCPMC13431521

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.