Evidence map›Paper›PMID 42514671›Full record

ArticleVeterinary sciences2026

Cross-Species Transmission and Recombination Between Feline and Canine Coronaviruses in Jiangsu-Zhejiang Region in 2025.

Yanhan Lin, Xiaoyang Zhu, Yifan Meng, Jiachun Zou, Wanying Xie, Shuai Yang, Meng Cui, Ming Qiu, Xinkai Wang, Qinchao Guan and 6 more

Abstract read
In one paragraph

Article in Veterinary sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Yanhan LinCollege of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.
Xiaoyang ZhuCollege of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.
Yifan MengCollege of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.
Jiachun ZouCollege of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.
Wanying XieCollege of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.
Shuai YangCollege of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.
Meng CuiCollege of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.
Ming QiuCollege of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.
Xinkai WangCollege of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.
Qinchao GuanCollege of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.
Hong LinCollege of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.
Sen JiangCollege of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.
Wanglong ZhengCollege of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.ORCID 0000-0002-0939-331X
Jianzhong ZhuCollege of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.ORCID 0000-0002-7082-1993
Kewei FanLongyan University and Fujian Provincial Key Laboratory for Prevention and Control of Animal Infectious Diseases and Biotechnology, Longyan 364012, China.
Nanhua ChenCollege of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.ORCID 0000-0002-1909-8760

Funding

the Open Project Program of Fujian Provincial Key Laboratory for Prevention and Control of Animal Infectious Diseases and Biotechnology ZDSYS2024001
6 · The paper itself

Abstract

Feline and canine coronaviruses (FCoVs and CCoVs) are widely prevalent in companion animals. The recent emergence of a highly virulent FCoV-CCoV recombinant virus, FCoV-23, caused a rapid feline infectious peritonitis (FIP) outbreak in Cyprus, which raises a serious concern about the cross-species transmission of CoVs among companion animals. Here, we evaluated the prevalence, transmission and evolution of FCoV and CCoV in the Jiangsu and Zhejiang provinces of China in 2025. A universal RT-qPCR assay for FCoV and CCoV was established and used for the detection of 700 clinical samples, including 501 from cats and 199 from dogs. A total of 92 samples (13.14%, 92/700) were detected as positive, containing 79 positive samples (15.76%, 79/501) from cats and 13 positive samples (6.5%, 13/199) from dogs. Ten complete S genes and two complete genomes were obtained from positive samples. Fragment comparison and phylogenetic analysis identified one CCoV-I sequence from a feline sample and one FCoV-II sequence from a canine sample. Furthermore, recombination analyses not only detected intra-species recombination events but also inter-species cross-over events. Collectively, this study, for the first time, revealed that cross-species transmission and recombination events occurred between FCoV and CCoV among companion animals in the Jiangsu-Zhejiang region of China in 2025.

Indexed as

canine coronavirus (CCoV)cross-species transmissionepidemiologyfeline coronavirus (FCoV)recombinationuniversal detection

Identifiers

PMID42514671
PMCPMC13431536

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.