Evidence map›Paper›PMID 42514348›Full record

ReviewNutrients2026

Higher-Protein Nutrition and Concurrent Exercise in Obesity: A Narrative Review of Body Composition, Metabolic Health, and Physical Function.

Claudia Reytor-González, Andrés Loor-Cedeño, Dolores Jima Gavilanes, Andri Matos, Juan Marcos Parise-Vasco, Jaime Angamarca-Iguago, Jaen Cagua-Ordoñez, Martín Campuzano-Donoso, Daniel Simancas-Racines

Abstract readReview
In one paragraph

Review in Nutrients, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Claudia Reytor-GonzálezCenter for Evidence Ecosystems, Implementation Science, and Decision-Making (CIDES), Facultad de Ciencias de la Salud y Bienestar Humano, Universidad Tecnológica Indoamérica, Ambato 180150, Ecuador.ORCID 0009-0007-4234-5524
Andrés Loor-CedeñoIndependent Researcher, Santo Domingo 230101, Ecuador.
Dolores Jima GavilanesEscuela de Medicina, Universidad Espíritu Santo, Samborondón 0901952, Ecuador.ORCID 0000-0003-0359-3617
Andri MatosSchool of Allied Health, Eastwick College, Ramsey, NJ 07446, USA.ORCID 0009-0009-8286-2475
Juan Marcos Parise-VascoCenter for Evidence Ecosystems, Implementation Science, and Decision-Making (CIDES), Facultad de Ciencias de la Salud y Bienestar Humano, Universidad Tecnológica Indoamérica, Quito 170103, Ecuador.ORCID 0000-0002-5223-3370
Jaime Angamarca-IguagoCenter for Evidence Ecosystems, Implementation Science, and Decision-Making (CIDES), Facultad de Ciencias de la Salud y Bienestar Humano, Universidad Tecnológica Indoamérica, Quito 170103, Ecuador.ORCID 0000-0003-1907-3632
Jaen Cagua-OrdoñezCenter for Evidence Ecosystems, Implementation Science, and Decision-Making (CIDES), Facultad de Ciencias de la Salud y Bienestar Humano, Universidad Tecnológica Indoamérica, Quito 170103, Ecuador.ORCID 0000-0002-1684-5206
Martín Campuzano-DonosoCenter for Evidence Ecosystems, Implementation Science, and Decision-Making (CIDES), Facultad de Ciencias de la Salud y Bienestar Humano, Universidad Tecnológica Indoamérica, Ambato 180150, Ecuador.ORCID 0000-0001-5317-8548
Daniel Simancas-RacinesCenter for Evidence Ecosystems, Implementation Science, and Decision-Making (CIDES), Facultad de Ciencias de la Salud y Bienestar Humano, Universidad Tecnológica Indoamérica, Ambato 180150, Ecuador.ORCID 0000-0002-3641-1501

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obesity care increasingly requires outcomes that extend beyond total body weight. Although weight reduction remains clinically meaningful, the scale alone does not indicate whether fat mass, lean tissue, muscle quality, strength, mobility, or physiological reserve have changed in a favorable direction. This narrative review examines the combined role of higher-protein dietary strategies and concurrent exercise in adults with obesity, with emphasis on body composition, metabolic health, and physical function. Higher-protein dietary strategies may support satiety, improve the tolerability of energy restriction in some patients, and attenuate lean-tissue loss during weight reduction, while evidence for superior long-term weight loss remains inconsistent. Exercise provides complementary stimuli to protein-focused nutrition: resistance training supports strength, muscle function, and lean-tissue preservation, while aerobic and interval-based training contribute to cardiorespiratory fitness, regional adiposity reduction, and selected cardiometabolic adaptations. Concurrent training offers a practical framework for integrating these stimuli, with value primarily as multidomain coverage rather than as evidence of universal superiority over other modalities. The main rationale for combining protein adequacy with exercise is preservation of usable physical function during weight loss, particularly in older adults, patients with sarcopenic-obesity risk, and individuals undergoing rapid pharmacological or surgical weight reduction. Overall, the available evidence is most consistent with viewing higher-protein nutrition and structured exercise as complementary strategies for improving the quality of weight loss, rather than as a single protocol for maximizing scale-weight reduction. Longer pragmatic trials are needed to clarify phenotype-specific responses, feasible protein targets, exercise progression, monitoring strategies, and functional outcomes.

Indexed as

Body CompositionDietary ProteinsDiet, High-ProteinExerciseObesityHumansWeight LossDietary Proteinsaerobic trainingbody compositionconcurrent exercisehigher-protein nutritionmetabolic healthnarrative reviewobesityphysical functionresistance trainingsarcopenic obesity

Identifiers

PMID42514348
PMCPMC13415002

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.