In one paragraphTrial report in Nutrients, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05503147 (A Pharmacological Trial With Sativex® and Gentamicin for Optimized Phamacological Treatment of Older Patients With Focus on Appetite Stimulation and Renal Risk Drugs), which is not on this map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Pharmacological Trial With Sativex® and Gentamicin for Optimized Phamacological Treatment of Older Patients With Focus on Appetite Stimulation and Renal Risk Drugs
TypeinterventionalSponsorOve AndersenRan2022 to 2023Enrolled17ConditionsMalnutrition, Anorexia, Cannabis, AgingArmsSativex
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
16 authors.
Olivia BornæsDepartment of Clinical Research, Copenhagen University Hospital Amager and Hvidovre, 2650 Hvidovre, Denmark.ORCID 0000-0002-5748-8153 Rikke Lundsgaard NielsenDepartment of Clinical Research, Copenhagen University Hospital Amager and Hvidovre, 2650 Hvidovre, Denmark.ORCID 0000-0003-2208-7349 Louise Westberg Strejby ChristensenDepartment of Clinical Research, Copenhagen University Hospital Amager and Hvidovre, 2650 Hvidovre, Denmark.ORCID 0009-0006-8954-2675 Ida Klitzing StorgaardDepartment of Clinical Research, Copenhagen University Hospital Amager and Hvidovre, 2650 Hvidovre, Denmark.
Thomas KallemoseDepartment of Clinical Research, Copenhagen University Hospital Amager and Hvidovre, 2650 Hvidovre, Denmark.ORCID 0000-0002-7356-6481 Helle Gybel Juul-LarsenDepartment of Clinical Research, Copenhagen University Hospital Amager and Hvidovre, 2650 Hvidovre, Denmark.ORCID 0000-0002-8543-9201 Juliette TavenierDepartment of Clinical Research, Copenhagen University Hospital Amager and Hvidovre, 2650 Hvidovre, Denmark.ORCID 0000-0002-2397-9974 Baker JawadDepartment of Clinical Research, Copenhagen University Hospital Amager and Hvidovre, 2650 Hvidovre, Denmark.ORCID 0000-0002-6915-744X Ove AndersenDepartment of Clinical Research, Copenhagen University Hospital Amager and Hvidovre, 2650 Hvidovre, Denmark.
Jens Juul HolstThe Novo Nordisk Foundation Center for Basic Metabolic Research, Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.ORCID 0000-0001-6853-3805 Bolette HartmannThe Novo Nordisk Foundation Center for Basic Metabolic Research, Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.ORCID 0000-0001-8509-2036 Aino Leegaard AndersenDepartment of Clinical Research, Copenhagen University Hospital Amager and Hvidovre, 2650 Hvidovre, Denmark.ORCID 0000-0003-1449-1931 Ingrid PoulsenDepartment of Clinical Research, Copenhagen University Hospital Amager and Hvidovre, 2650 Hvidovre, Denmark.ORCID 0000-0002-0342-017X David Peick SonneDepartment of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.
Morten Baltzer HoulindDepartment of Clinical Research, Copenhagen University Hospital Amager and Hvidovre, 2650 Hvidovre, Denmark.ORCID 0000-0003-4058-3012 Mette Merete PedersenDepartment of Clinical Research, Copenhagen University Hospital Amager and Hvidovre, 2650 Hvidovre, Denmark.ORCID 0000-0001-5719-2531 Funding
A.P. Møller Fund for the Advancement of Medical Science 19-L-0217Beckett-Fonden 24-2-13188Danish Regions 2627
6 · The paper itselfAbstract
backgroundPoor appetite, a major contributor to malnutrition, is highly prevalent among older adults and associated with adverse clinical outcomes. Nevertheless, there are currently no widely accepted or consistently effective pharmacological treatments targeting appetite that are routinely recommended alongside nutritional interventions. Medical cannabis has been proposed as a potential appetite stimulant in older adults with poor appetite through modulation of appetite-regulating hormones such as glucagon-like peptide-1 (GLP-1) and total ghrelin, but the evidence remains limited.
aimsTo investigate the effects of Sativex
methodsThis protocolized secondary analysis included 17 participants (≥65 years) with poor appetite from a double-blind, randomized, placebo-controlled crossover trial. Participants received Sativex
resultsCompared with placebo, Sativex
conclusionsIn conclusion, no statistically significant differences were detected between Sativex
trial registrationClinicalTrials.gov ID: NCT05503147; EudraCT nr.: 2021-002318-15.
Indexed as
AppetiteAppetite StimulantsCannabidiolDronabinolGhrelinGlucagon-Like Peptide 1Medical MarijuanaAgedAged, 80 and overCross-Over StudiesDouble-Blind MethodDrug CombinationsFemaleHumansMalePostprandial PeriodAppetite StimulantsCannabidiolDronabinolDrug CombinationsGhrelinGlucagon-Like Peptide 1Medical Marijuanamalnutritionolder adultspoor appetite, cannabis-based medicine, Sativex®, glucagon-like peptide-1, ghrelin, hospital
Identifiers
PMID42514343
PMCPMC13414925
What OpenQuestion holds
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LicenceCC BY
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