Evidence map›Paper›PMID 42514296›Full record

ReviewNutrients2026

Vitamin D Deficiency in Leukemia: Implications for Pathophysiology, Treatment, and Supportive Care.

Zahra Eskandari, Ireneusz Ryszkiel, Amirhossein Faghih Ojaroodi, Haniyeh Bazavar, Shayan Keramat, Agata Stanek

Abstract readReview
In one paragraph

Review in Nutrients, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zahra EskandariDepartment of Hematology, Faculty of Allied Medicine, Bushehr University of Medical Sciences, Bushehr 7514633341, Iran.ORCID 0009-0004-9326-436X
Ireneusz RyszkielDepartment of Internal Medicine, Metabolic Diseases and Angiology, Faculty of Health Sciences in Katowice, Medical University of Silesia, Ziołowa 45/47, 40-635 Katowice, Poland.ORCID 0000-0002-7365-6014
Amirhossein Faghih OjaroodiStudent Research Committee, Tabriz University of Medical Sciences, Tabriz 5165665931, Iran.ORCID 0009-0001-0703-6511
Haniyeh BazavarDepartment of Hematology, Zanjan University of Medical Science, Zanjan 4513956184, Iran.ORCID 0000-0002-1703-9847
Shayan KeramatVAS-European Independent Foundation in Angiology/Vascular Medicine, Via GB Grassi 74, 20157 Milan, Italy.ORCID 0000-0002-0612-9978
Agata StanekDepartment of Internal Medicine, Metabolic Diseases and Angiology, Faculty of Health Sciences in Katowice, Medical University of Silesia, Ziołowa 45/47, 40-635 Katowice, Poland.ORCID 0000-0001-6939-9898

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Leukemia represents a heterogeneous group of hematologic malignancies characterized by the dysregulated proliferation, differentiation, and survival of hematopoietic cells. Vitamin D (VD), a fat-soluble secosteroid hormone, is increasingly recognized not only as a regulator of calcium-phosphate metabolism but also as an important immune-metabolic modulator involved in hematopoietic homeostasis, inflammatory signaling, and cellular fate determination. Growing evidence suggests that VD deficiency may influence leukemogenesis, disease progression, treatment responsiveness, and supportive-care outcomes in patients with leukemia. Mechanistic studies indicate that the active metabolite, 1,25-dihydroxyvitamin D

Indexed as

LeukemiaVitamin DVitamin D DeficiencyHumansReceptors, CalcitriolSignal Transduction25-hydroxyvitamin DReceptors, CalcitriolVitamin Dfat-soluble vitaminshematopoietic homeostasisimmune–metabolic regulationleukemiaprecision nutritionsupplementationsupportive carevitamin Dvitamin D receptor signaling

Identifiers

PMID42514296
PMCPMC13414498

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.