Evidence map›Paper›PMID 42514083›Full record

ArticleMicroorganisms2026

The Cyclic Di-GMP Receptor HpoR Modulates Mycobacterial Multidrug Susceptibility by Regulating IniBAC-Mediated Envelope Permeability.

Xiao Liu, Xiaocui Ling, Kun Wang, Jiachen Zheng, Hao Li, Minhao Guo, Yanzhe Ou, Jie Lu, Weihui Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microorganisms, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xiao LiuState Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, Guangxi Technology Innovation Center for Microbial Resources Development and Utilization, College of Life Science and Technology, Guangxi University, Nanning 530004, China.
Xiaocui LingState Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, Guangxi Technology Innovation Center for Microbial Resources Development and Utilization, College of Life Science and Technology, Guangxi University, Nanning 530004, China.ORCID 0009-0003-5489-5452
Kun WangState Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, Guangxi Technology Innovation Center for Microbial Resources Development and Utilization, College of Life Science and Technology, Guangxi University, Nanning 530004, China.
Jiachen ZhengState Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, Guangxi Technology Innovation Center for Microbial Resources Development and Utilization, College of Life Science and Technology, Guangxi University, Nanning 530004, China.
Hao LiState Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, Guangxi Technology Innovation Center for Microbial Resources Development and Utilization, College of Life Science and Technology, Guangxi University, Nanning 530004, China.
Minhao GuoState Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, Guangxi Technology Innovation Center for Microbial Resources Development and Utilization, College of Life Science and Technology, Guangxi University, Nanning 530004, China.ORCID 0009-0008-7185-0922
Yanzhe OuState Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, Guangxi Technology Innovation Center for Microbial Resources Development and Utilization, College of Life Science and Technology, Guangxi University, Nanning 530004, China.
Jie LuState Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, Guangxi Technology Innovation Center for Microbial Resources Development and Utilization, College of Life Science and Technology, Guangxi University, Nanning 530004, China.
Weihui LiState Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, Guangxi Technology Innovation Center for Microbial Resources Development and Utilization, College of Life Science and Technology, Guangxi University, Nanning 530004, China.ORCID 0000-0001-7037-7610

Funding

Guangxi Science and Technology Department 2022JJG130005National Natural Science Foundation of China 32360013National Natural Science Foundation of China 32470034
6 · The paper itself

Abstract

Isoniazid (INH) targets cell wall biosynthesis and is a potent antimycobacterial agent. Elucidating the regulatory networks that govern drug susceptibility in mycobacterial models is fundamental to understanding intrinsic resistance in pathogenic species. The

Indexed as

c-di-GMPenvelope permeabilitymultidrug susceptibilitymycobacteriatranscriptional regulation

Identifiers

PMID42514083
PMCPMC13413693

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.