ArticleMicroorganisms2026
Global Research Trends on Polyhydroxyalkanoate-Producing Microorganisms: A Bibliometric and Scientometric Analysis of Sustainable Bioplastic Biotechnology.
Article in Microorganisms, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This scientometric and bibliometric study analyzes global research trends on polyhydroxyalkanoate (PHA)-producing microorganisms and their applications in bio-based packaging between 2014 and 2025. Using the Scopus database and advanced tools such as Bibliometrix in RStudio and VOSviewer, scientific output and international collaboration networks were evaluated. The results demonstrate exponential growth in publications, driven by the urgent need to mitigate the petrochemical plastics crisis and develop biodegradable alternatives within the circular economy. Multidisciplinary analysis reveals a thematic shift from basic physiological and taxonomic studies towards complex applications in metabolic engineering, synthetic biology, the optimization of low-cost substrates such as industrial effluents, multi-omics tools, gene editing with CRISPR-Cas9, and, as an emerging exploratory approach, quantum modeling to optimize cell performance. Despite significant progress, critical technological gaps were identified related to challenges in downstream processing, the management of mixed microbial communities, and insufficient funding for the characterization of physicochemical and biocompatibility properties. It is concluded that, to ensure the commercial scalability and sustainability of PHAs, future research must prioritize overcoming these economic and technological bottlenecks, fostering strategic collaboration between academia and the biotechnology industry.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.