ArticleMicroorganisms2026
Do Treponemes in Bovine Digital Dermatitis-Associated Claw Horn Lesions Preclude Co-Infection by Pyogenic Bacteria?
Article in Microorganisms, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
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Abstract
Bovine digital dermatitis (BDD) is an infectious claw disease chiefly induced by treponemes, while deep digital sepsis (DDS) is caused by pyogenic bacteria. It is currently unclear why persistent BDD-associated claw horn lesions (BDD-CHL) do not develop DDS. One possible explanation could be that the intralesional presence of treponemes makes it more difficult for pyogenic bacteria to colonize BDD-CHL. To lay the groundwork for exploring this possibility, we determined the presence and amounts of treponemes and selected pyogenic bacteria in BDD-CHL versus DDS at the DNA level. "Total Treponema" (TT-)PCR and type-specific qPCR were used to screen 18 BDD-CHLs from 15 cows and 18 DDS samples from 11 cows for bacterial DNA. TT-PCR identified
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