Metagenomic Insights into the Seasonal Distribution and Dissemination Risks of Biocide and Metal Resistance Genes in a Subtropical Coastal Ecosystem.

Lihong Gan, Shiyun Fang, Hengsong Wu, Tianhao Yao, Wenjian Chen, Yusen Li, Yaoquan Han, Lei Zhou

Abstract read

In one paragraph

Article in Microorganisms, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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5 · Who and what money

Authors and funding

8 authors.

Lihong GanUniversity Joint Laboratory of Guangdong Province, Hong Kong and Macao Region on Marine Bioresource Conservation and Exploitation, College of Marine Sciences, South China Agricultural University, Guangzhou 510642, China.

Shiyun FangUniversity Joint Laboratory of Guangdong Province, Hong Kong and Macao Region on Marine Bioresource Conservation and Exploitation, College of Marine Sciences, South China Agricultural University, Guangzhou 510642, China.

Hengsong WuUniversity Joint Laboratory of Guangdong Province, Hong Kong and Macao Region on Marine Bioresource Conservation and Exploitation, College of Marine Sciences, South China Agricultural University, Guangzhou 510642, China.

Tianhao YaoUniversity Joint Laboratory of Guangdong Province, Hong Kong and Macao Region on Marine Bioresource Conservation and Exploitation, College of Marine Sciences, South China Agricultural University, Guangzhou 510642, China.

Wenjian ChenKey Laboratory of Aquaculture Genetic and Breeding and Healthy Aquaculture of Guangxi, Guangxi Academy of Fishery Sciences, Nanning 530021, China.

Yusen LiKey Laboratory of Aquaculture Genetic and Breeding and Healthy Aquaculture of Guangxi, Guangxi Academy of Fishery Sciences, Nanning 530021, China.

Yaoquan HanKey Laboratory of Aquaculture Genetic and Breeding and Healthy Aquaculture of Guangxi, Guangxi Academy of Fishery Sciences, Nanning 530021, China.

Lei ZhouUniversity Joint Laboratory of Guangdong Province, Hong Kong and Macao Region on Marine Bioresource Conservation and Exploitation, College of Marine Sciences, South China Agricultural University, Guangzhou 510642, China.ORCID 0000-0002-3995-1087

Funding

Ministry of Agriculture and Rural Affairs No. GXKEYLA-2023-01-1

6 · The paper itself

Abstract

The widespread use of antimicrobial biocides and metals has led to the continuous accumulation of biocide and metal resistance genes (BMRGs) in the environment. The issue is of growing concern, as it reduces the efficacy of these agents and poses a potential threat to coastal ecological security. However, the extent of coastal BMRG pollution, its transmission mechanisms, and the influence of seasonal variations on its assembly remain poorly understood. In this study, metagenomic sequencing was employed to investigate BMRGs, microbiomes, and mobile genetic elements (MGEs) within the subtropical nearshore ecosystem of the Beibu Gulf during the autumn and winter seasons. A total of 33 BMRG types and 457 subtypes were detected, with higher subtype diversity in winter than in autumn (440 vs. 326 subtypes). Notably, genes resistant to multi-biocides exhibited the highest diversity, whereas those resistant to both biocides and metals were the most abundant. Co-occurrence network analysis showed that 22 of the 23 detected BMRGs in the winter network were associated with MGEs, especially transposase-related elements such as

Indexed as

Beibu Gulfbiocide and metal resistance geneshorizontal gene transfermobile genetic elementsseasonal variations

Identifiers

PMID42513986

DOI10.3390/microorganisms14071480

PMCPMC13414413

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.