Evidence map›Paper›PMID 42513925›Full record

ArticleMicroorganisms2026

A Meta-Analysis of the Protective Efficacy of

Jing Yuan, Maoyuan Gu, Rongrong Ni, Xufeng Liu, Qimin Dong, Mengdi Dong, Shuqi Dong, Zeyao Wang, Tianyue Zhang, Yuting Zhang and 8 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microorganisms, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Jing YuanCollege of Animal Science and Technology, Shihezi University, Shihezi 832003, China.ORCID 0009-0004-1739-6918
Maoyuan GuCollege of Animal Science and Technology, Shihezi University, Shihezi 832003, China.ORCID 0009-0002-7125-4457
Rongrong NiCollege of Animal Science and Technology, Shihezi University, Shihezi 832003, China.ORCID 0009-0009-0215-7507
Xufeng LiuSchool of Clinical Medicine, Shihezi University, Shihezi 832003, China.ORCID 0009-0001-5038-1943
Qimin DongCollege of Animal Science and Technology, Shihezi University, Shihezi 832003, China.ORCID 0009-0007-3129-7600
Mengdi DongCollege of Animal Science and Technology, Shihezi University, Shihezi 832003, China.ORCID 0009-0009-0901-4082
Shuqi DongCollege of Animal Science and Technology, Shihezi University, Shihezi 832003, China.ORCID 0009-0004-5600-928X
Zeyao WangCollege of Animal Science and Technology, Shihezi University, Shihezi 832003, China.ORCID 0009-0008-9749-2828
Tianyue ZhangCollege of Animal Science and Technology, Shihezi University, Shihezi 832003, China.ORCID 0009-0002-3521-1492
Yuting ZhangCollege of Animal Science and Technology, Shihezi University, Shihezi 832003, China.ORCID 0009-0004-0691-5954
Zhujie FuCollege of Animal Science and Technology, Shihezi University, Shihezi 832003, China.ORCID 0009-0005-5156-7626
Junyuan LiCollege of Animal Science and Technology, Shihezi University, Shihezi 832003, China.ORCID 0009-0002-8230-3875
Yanbing ZhangCollege of Animal Science and Technology, Shihezi University, Shihezi 832003, China.ORCID 0009-0003-9564-3999
Huan ZhangCollege of Animal Science and Technology, Shihezi University, Shihezi 832003, China.ORCID 0000-0001-9366-2385
Zhongchen MaCollege of Animal Science and Technology, Shihezi University, Shihezi 832003, China.ORCID 0000-0002-3951-4610
Junbo ZhangGuizhou Provincial Key Laboratory for Biodiversity Conservation and Utilization in the Fanjing Mountain Region, Tongren University, Tongren 554300, China.
Jihai YiCollege of Animal Science and Technology, Shihezi University, Shihezi 832003, China.ORCID 0009-0002-7954-5136
Yueli WangSchool of Clinical Medicine, Shihezi University, Shihezi 832003, China.ORCID 0000-0001-5320-4953

Funding

Open Project of Key Laboratory of Animal Biopharmaceutical Corps FM0F2024001Open Project Program of Jiangsu Key Laboratory of Zoonosis R2104Shihezi University Research Startup Program for High-Level Talents RCZK202573Sichuan Regional Innovation Cooperation Project No. 2026YFHZ0179the Tongren Science and Technology Bureau Project TSKY[2023]39, TSKY[2024]6the Youth Outstanding Science and Technology Talent Project of Department of Education of Guizhou Province QJJ[2024]347
6 · The paper itself

Abstract

Brucellosis remains a major zoonotic disease that affects both public health and animal production worldwide. Conventional live vaccines, including S19, RB51, and A19, are commonly used for disease control; however, concerns regarding their safety and performance under field conditions limit their application. Targeted gene deletion in

Indexed as

Brucellaconventional vaccinesgene-deletion mutantsmeta-analysisprotective efficacy

Identifiers

PMID42513925
PMCPMC13413911

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.