Evidence map›Paper›PMID 42513221›Full record

ArticleMolecules (Basel, Switzerland)2026

Structural Improvement of the Allosteric ALOX15 Inhibitor Octyl (

Viktor Gavrilyuk, Vladislav Aksenov, Kirill Petrov, Angelina V Kurchatova, Dmitriy Bortnevskij, Alexander Zhuravlev, Alexey Golovanov, Hartmut Kuhn, Igor Ivanov

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Viktor GavrilyukLomonosov Institute of Fine Chemical Technologies, MIREA-Russian Technological University, Vernadskogo pr. 86, 119571 Moscow, Russia.ORCID 0000-0002-1811-2380
Vladislav AksenovLomonosov Institute of Fine Chemical Technologies, MIREA-Russian Technological University, Vernadskogo pr. 86, 119571 Moscow, Russia.ORCID 0009-0002-7720-061X
Kirill PetrovLomonosov Institute of Fine Chemical Technologies, MIREA-Russian Technological University, Vernadskogo pr. 86, 119571 Moscow, Russia.ORCID 0009-0001-8239-6277
Angelina V KurchatovaLomonosov Institute of Fine Chemical Technologies, MIREA-Russian Technological University, Vernadskogo pr. 86, 119571 Moscow, Russia.
Dmitriy BortnevskijLomonosov Institute of Fine Chemical Technologies, MIREA-Russian Technological University, Vernadskogo pr. 86, 119571 Moscow, Russia.
Alexander ZhuravlevLomonosov Institute of Fine Chemical Technologies, MIREA-Russian Technological University, Vernadskogo pr. 86, 119571 Moscow, Russia.
Alexey GolovanovLomonosov Institute of Fine Chemical Technologies, MIREA-Russian Technological University, Vernadskogo pr. 86, 119571 Moscow, Russia.
Hartmut KuhnInstitute of Biochemistry, Charite-University Medicine Berlin, Corporate Member of Free University Berlin, Humboldt University Berlin and Berlin Institute of Health, Charitéplatz 1, 10117 Berlin, Germany.ORCID 0000-0001-8142-3192
Igor IvanovLomonosov Institute of Fine Chemical Technologies, MIREA-Russian Technological University, Vernadskogo pr. 86, 119571 Moscow, Russia.ORCID 0000-0003-0543-2067

Funding

Russian Ministry of Science and High Education FSFZ-2026-0007
6 · The paper itself

Abstract

Octyl (

Indexed as

Arachidonate 15-LipoxygenaseIndolesLipoxygenase InhibitorsAllosteric RegulationAnimalsHumansMolecular StructureRabbitsStructure-Activity RelationshipArachidonate 15-LipoxygenaseIndolesLipoxygenase Inhibitorsallosteryheterocyclic compoundsinhibitorslipid metabolismlipoxygenases

Identifiers

PMID42513221
PMCPMC13415832

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.