ReviewMolecules (Basel, Switzerland)2026
Research Progress on Nicotine Control Methods in Tobacco Products.
Review in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This paper systematically reviews recent research progress on nicotine control methods in tobacco products, with a focus on various strategies including the regulation of internal tobacco components (such as organic acids, pH, polyols, and moisture content) and the application of external functional materials (e.g., bacterial cellulose-based sustained-release systems and MOF composites). The mechanisms and control efficacy of these approaches are elaborated, along with a comparative analysis of their applicable conditions and limitations. Furthermore, emerging research directions in the precise control of nicotine release are discussed, including multi-factor coupling regulation, material structure design, and release kinetic modeling. By systematically examining the strengths and weaknesses of existing technologies, product-specific and condition-dependent internal control strategies are summarized for different tobacco products based on the available evidence. Finally, future prospects are outlined, including the development of intelligent sustained-release materials, the construction of multi-path synergistic regulation systems, and the integration of toxicological assessments to achieve comprehensive optimization of product quality and health risks. This review aims to provide a mechanistic basis for the rational design of nicotine release control strategies in tobacco products.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.