ArticleMolecules (Basel, Switzerland)2026
KI17: A Bioinspired Peptide Derived from
Ana Paula Ramos Pereira, Ana Cristina Jacobowski, Camila de Oliveira Gutierrez, Octávio Luiz Franco, Marlon Henrique Cardoso, Thaís de Andrade Farias Rodrigues, Rodrigo Juliano Oliveira, Priscila Aiko Hiane, Rita de Cássia Avellaneda Guimarães, Ana Paula de Araújo Boleti and 1 more
Abstract read
In one paragraphArticle in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
11 authors.
Ana Paula Ramos PereiraLaboratory of Protein Purification and Biological Functions, FACFAN, Federal University of Mato Grosso do Sul, Campo Grande 79070-900, MS, Brazil.ORCID 0000-0002-9620-861X Ana Cristina JacobowskiLaboratory of Protein Purification and Biological Functions, FACFAN, Federal University of Mato Grosso do Sul, Campo Grande 79070-900, MS, Brazil.ORCID 0000-0001-8233-0713 Camila de Oliveira GutierrezLaboratory of Protein Purification and Biological Functions, FACFAN, Federal University of Mato Grosso do Sul, Campo Grande 79070-900, MS, Brazil.
Octávio Luiz FrancoS-Inova Biotech, Graduate Program in Biotechnology, Dom Bosco Catholic University, Campo Grande 79117-900, MS, Brazil.
Marlon Henrique CardosoCenter for Proteomic and Biochemical Analysis, Graduate Program in Genomic Sciences and Biotechnology, Catholic University of Brasília, Brasília 71966-700, DF, Brazil.ORCID 0000-0001-6676-5362 Thaís de Andrade Farias RodriguesCeTroGen Laboratory, Universidade Federal de Mato Grosso do Sul, Campo Grande 79070-900, MS, Brazil.ORCID 0000-0002-1937-0162 Rodrigo Juliano OliveiraCeTroGen Laboratory, Universidade Federal de Mato Grosso do Sul, Campo Grande 79070-900, MS, Brazil.ORCID 0000-0003-3514-3346 Priscila Aiko HianeFaculty of Pharmaceutical Sciences, Food and Nutrition, Universidade Federal de Mato Grosso do Sul, Campo Grande 79070-900, MS, Brazil.ORCID 0000-0003-1115-4083 Rita de Cássia Avellaneda GuimarãesFaculty of Pharmaceutical Sciences, Food and Nutrition, Universidade Federal de Mato Grosso do Sul, Campo Grande 79070-900, MS, Brazil.
Ana Paula de Araújo BoletiLaboratory of Protein Purification and Biological Functions, FACFAN, Federal University of Mato Grosso do Sul, Campo Grande 79070-900, MS, Brazil.
Maria Lígia Rodrigues MacedoLaboratory of Protein Purification and Biological Functions, FACFAN, Federal University of Mato Grosso do Sul, Campo Grande 79070-900, MS, Brazil.ORCID 0000-0001-6969-6307 Funding
Conselho Nacional de Desenvolvimento Científico e Tecnológico CNPq, grant 314858/2020-2Financiadora de Estudos e Projetos FINEP, grant 01.19.0124.00Fundação de Apoio ao Desenvolvimento do Ensino, Ciência e Tecnologia do Estado de Mato Grosso do Sul FUNDECT, grant 71/020.508/2022
6 · The paper itselfAbstract
Cancer therapy remains limited by drug resistance and poor selectivity, while inflammation-driven tumor progression further complicates treatment outcomes. Antimicrobial peptides (AMPs) have emerged as promising therapeutic alternatives due to their multifunctional properties. In this study, we investigated the anticancer and immunomodulatory activities of KI17, a rationally designed peptide derived from GL18, a peptide fragment identified from the talisin protein of
Indexed as
Antineoplastic AgentsImmunologic FactorsImmunomodulating AgentsPeptidesAnimalsApoptosisCell Line, TumorCell ProliferationCell SurvivalHeLa CellsHumansMiceNitric OxideAntineoplastic AgentsImmunologic FactorsImmunomodulating AgentsNitric OxidePeptidescell cycle arrestmelanomamitochondrial apoptosisrational peptide design
Identifiers
PMID42513118
PMCPMC13415284
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