Evidence map›Paper›PMID 42512811›Full record

ReviewMedicina (Kaunas, Lithuania)2026

Targeting Sleep to Improve Outcomes in Psychosis: Digital and Non-Pharmacological Interventions.

Valentina Baldini, Martina Gnazzo, Giorgia Varallo, Diana De Ronchi, Lorenzo Pelizza, Marco Menchetti, Giuseppe Plazzi

Abstract readReview
In one paragraph

Review in Medicina (Kaunas, Lithuania), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Valentina BaldiniDepartment of Biomedical and Neuromotor Sciences, University of Bologna, 40126 Bologna, Italy.
Martina GnazzoClinic of Child and Adolescent Neuropsychiatry, Department of Mental Health, Physical and Preventive Medicine, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.
Giorgia VaralloDepartment of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.
Diana De RonchiDepartment of Biomedical and Neuromotor Sciences, University of Bologna, 40126 Bologna, Italy.ORCID 0000-0002-2913-0621
Lorenzo PelizzaDepartment of Biomedical and Neuromotor Sciences, University of Bologna, 40126 Bologna, Italy.ORCID 0000-0003-4746-2061
Marco MenchettiDepartment of Biomedical and Neuromotor Sciences, University of Bologna, 40126 Bologna, Italy.
Giuseppe PlazziIRCCS Istituto Delle Scienze Neurologiche di Bologna (ISNB), 40139 Bologna, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sleep disturbances are among the most prevalent and clinically significant features observed across the psychosis spectrum, ranging from clinical high-risk (CHR) mental states to first-episode psychosis (FEP) and chronic schizophrenia. Far from being merely secondary phenomena, sleep difficulties-including insomnia, circadian rhythm disruption, altered sleep architecture, hypersomnia, and nightmare disorder-are increasingly acknowledged as transdiagnostic risk factors that may contribute to symptom severity, cognitive impairment, functional decline, and heightened suicidal risk. This narrative review consolidates current evidence on the epidemiology and neurobiological foundations of sleep disturbances in the psychosis spectrum and critically evaluates available non-pharmacological and digital interventions aimed at targeting sleep as a modifiable clinical outcome. We posit that sleep represents a critical, potentially modifiable intervention target within psychosis and that integrating sleep-focused care into standard clinical pathways may substantially enhance clinical, functional, and safety outcomes throughout the illness spectrum, pending replication in adequately powered randomized controlled trials.

Indexed as

Psychotic DisordersSleepSleep Wake DisordersDigital HealthHumansSchizophreniaclinical high-riskfirst-episode psychosisinsomniapsychosisschizophreniasleep

Identifiers

PMID42512811
PMCPMC13413458

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.