Evidence map›Paper›PMID 42512453›Full record

ArticleBrain sciences2026

CP5-Centered Parietal HD-tACS Is Associated with Improved Performance in a Smartphone-Based Shopping Task in Older Adults: A Behavioral and EEG Investigation.

Jiabao Hu, Yuhao Zhu, Mengdie Wang, Xiaorong Cheng, Xianfeng Ding, Zhao Fan

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Article in Brain sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Jiabao HuKey Laboratory of Adolescent Cyberpsychology and Behavior (CCNU), Ministry of Education, Wuhan 430079, China.
Yuhao ZhuKey Laboratory of Adolescent Cyberpsychology and Behavior (CCNU), Ministry of Education, Wuhan 430079, China.
Mengdie WangKey Laboratory of Adolescent Cyberpsychology and Behavior (CCNU), Ministry of Education, Wuhan 430079, China.
Xiaorong ChengKey Laboratory of Adolescent Cyberpsychology and Behavior (CCNU), Ministry of Education, Wuhan 430079, China.ORCID 0000-0001-6097-4382
Xianfeng DingKey Laboratory of Adolescent Cyberpsychology and Behavior (CCNU), Ministry of Education, Wuhan 430079, China.ORCID 0000-0002-5815-7313
Zhao FanKey Laboratory of Adolescent Cyberpsychology and Behavior (CCNU), Ministry of Education, Wuhan 430079, China.ORCID 0000-0002-8683-2873

Funding

the National Social Science Fund of China 21BSH107
6 · The paper itself

Abstract

BACKGROUND/

objectivesOlder adults often experience difficulties in smartphone use, especially when digital tasks require goal maintenance, visual search, sequential action, and response verification. Working memory and parietal theta-band activity may support these cognitively demanding operations, but it remains unclear whether a single session of theta-frequency high-definition transcranial alternating current stimulation (HD-tACS), centered over CP5 as a parietal scalp location intended to approximate the left inferior parietal region, is associated with short-term changes in smartphone-task performance in aging.

methodsThis study examined performance in a controlled smartphone-based shopping task and exploratory post-stimulation EEG correlates. In Experiment 1, 40 older adults were randomly assigned to active HD-tACS or sham stimulation. In Experiment 2, 28 older adults completed a reduced-trial EEG extension of the same task with electroencephalography (EEG) recording before and after stimulation.

resultsActive stimulation improved smartphone-task performance, including faster completion under high cognitive load, higher target selection accuracy, and reduced difficulty-time slope. Working-memory performance on a two-back task was also improved, and individual differences in working-memory gains were associated with improvements in smartphone-task efficiency. Active HD-tACS most strongly improved target selection accuracy, and exploratory post-stimulation theta-power changes in posterior/parietal regions may have accompanied high-demand target-selection-accuracy improvement. These neural findings should be interpreted cautiously because the omnibus EEG effects were trend-level, EEG-behavior correlations were based on a small active-stimulation subgroup, data-quality sensitivity analyses indicated artifact-related instability in theta-power estimates, and the full exploratory EEG-behavior correlation matrix did not survive FDR correction.

conclusionsThese findings provide short-term behavioral evidence that CP5-centered parietal HD-tACS may support performance in a cognitively demanding smartphone-based task and motivate further work at the intersection of neuromodulation, cognitive aging, and human-technology interaction.

Indexed as

EEGHD-tACSolder adultssmartphone-task performanceworking memory

Identifiers

PMID42512453
PMCPMC13406462

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.