Evidence map›Paper›PMID 42512293›Full record

ArticleCancers2026

Prognostic Value of the Combined Lymphocyte-to-Monocyte Ratio and Handgrip Strength in Patients with Resected Pancreatic Head Cancer.

Kazushi Yamashita, Daisuke Suzuki, Katsunori Furukawa, Tsukasa Takayashiki, Satoshi Kuboki, Shigetsugu Takano, Masayuki Ohtsuka

Abstract read
In one paragraph

Article in Cancers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Kazushi YamashitaDepartment of General Surgery, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan.
Daisuke SuzukiDepartment of Surgery, Teikyo University Chiba Medical Center, Ichihara 299-0111, Chiba, Japan.ORCID 0000-0001-7316-5672
Katsunori FurukawaDepartment of Surgery, National Hospital Organization Chiba Medical Center, Chiba 260-8606, Japan.
Tsukasa TakayashikiDepartment of General Surgery, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan.
Satoshi KubokiDepartment of General Surgery, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan.
Shigetsugu TakanoDepartment of General Surgery, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan.ORCID 0000-0002-6495-0422
Masayuki OhtsukaDepartment of General Surgery, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesThe lymphocyte-to-monocyte ratio (LMR) is an inflammation-based prognostic score (IBPS) that can be easily calculated using routine blood tests. Handgrip strength (HGS), a key diagnostic component of sarcopenia, also predicts survival. Nonetheless, the prognostic role of combined LMR and HGS in patients with pancreatic head cancer undergoing pancreaticoduodenectomy remains unclear. This exploratory study aimed to analyze whether the combination of preoperative LMR and HGS is associated with overall survival.

methodsWe retrospectively analyzed 105 patients with pancreatic head cancer who underwent pancreaticoduodenectomy at Chiba University Hospital from January 2016 to December 2020. We examined the prognostic values of IBPSs and HGS and compared combinations of preoperatively measurable factors.

resultsMultivariate analysis assessing preoperatively measurable factors demonstrated that low preoperative HGS, low preoperative LMR, and high preoperative carbohydrate antigen 19-9 level were associated with poor overall survival (hazard ratio [HR]: 2.41, 95% confidence interval [CI]: 1.29-4.51,

conclusionsIn this single-center exploratory study, the combination of preoperative LMR and HGS was associated with poor overall survival in patients with surgically resected pancreatic head cancer. Further prospective multicenter validation is required before this combined marker can be used for clinical decision-making.

Indexed as

handgrip strengthinflammation-based prognostic scorelymphocyte-to-monocyte ratiopancreatic head cancerpancreaticoduodenectomysarcopenia

Identifiers

PMID42512293
PMCPMC13406391

What OpenQuestion holds

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LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.