Evidence map›Paper›PMID 42512072›Full record

ArticleBiomedicines2026

Expression of Thymidylate Synthase in Cancer: A Tissue Microarray Study Involving 17,371 Cancers from 136 Tumor Entities.

Florian Lutz, Lisa Sophie Hannemann, Seyma Büyücek, Katharina Möller, Florian Viehweger, Ria Schlichter, Andreas M Luebke, Martina Kluth, Claudia Hube-Magg, Andrea Hinsch and 15 more

Abstract read
In one paragraph

Article in Biomedicines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Florian LutzInstitute of Pathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Lisa Sophie HannemannInstitute of Pathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Seyma BüyücekInstitute of Pathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.ORCID 0000-0002-9106-6595
Katharina MöllerInstitute of Pathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Florian ViehwegerInstitute of Pathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Ria SchlichterInstitute of Pathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Andreas M LuebkeInstitute of Pathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.ORCID 0000-0003-1464-6964
Martina KluthInstitute of Pathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Claudia Hube-MaggInstitute of Pathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.ORCID 0000-0001-7542-4340
Andrea HinschInstitute of Pathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Christian BernreutherInstitute of Pathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Guido SauterInstitute of Pathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.ORCID 0000-0002-9024-4978
David DumInstitute of Pathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.ORCID 0000-0002-7884-4313
Andreas H MarxDepartment of Pathology, Academic Hospital Fuerth, 90766 Fuerth, Germany.
Ronald SimonInstitute of Pathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.ORCID 0000-0003-0158-4258
Till KrechInstitute of Pathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Till S ClauditzInstitute of Pathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.ORCID 0000-0002-4257-856X
Frank JacobsenInstitute of Pathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Eike BurandtInstitute of Pathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Stefan SteurerInstitute of Pathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Patrick LebokInstitute of Pathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.ORCID 0000-0003-3652-532X
Christoph FrauneInstitute of Pathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Sarah MinnerInstitute of Pathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.ORCID 0000-0003-0765-3568
Natalia GorbokonInstitute of Pathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Maximilian LennartzInstitute of Pathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.ORCID 0000-0002-1572-8200

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

immunohistochemistrymultitumor analysisthymidylate synthasetissue microarraytumor phenotypeTYMS

Identifiers

PMID42512072
PMCPMC13406595

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.