Evidence map›Paper›PMID 42512037›Full record

ArticleBiomedicines2026

The Poly-Arginine Peptide R18D Inhibits Amyloid-Beta (Aβ) Aggregation and Aβ-Induced Cytotoxicity, Reduces Intracellular Tau Aggregation, and Exhibits Oral Bioavailability.

Vaishali Bagda, Zainab H Farooz, Neville W Knuckey, Samantha M South, Stuart K Gribble, Maitri Tomar, Prashant Bharadwaj, Ajish Ariyath, Kevin Taddei, Ralph N Martins and 1 more

Abstract read
In one paragraph

Article in Biomedicines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Vaishali BagdaPerron Institute for Neurological and Translational Science, Nedlands, WA 6009, Australia.ORCID 0009-0004-6222-7785
Zainab H FaroozPerron Institute for Neurological and Translational Science, Nedlands, WA 6009, Australia.
Neville W KnuckeyPerron Institute for Neurological and Translational Science, Nedlands, WA 6009, Australia.
Samantha M SouthArgenica Therapeutics, Nedlands, WA 6009, Australia.
Stuart K GribbleArgenica Therapeutics, Nedlands, WA 6009, Australia.
Maitri TomarPerron Institute for Neurological and Translational Science, Nedlands, WA 6009, Australia.ORCID 0000-0003-4766-2768
Prashant BharadwajCentre of Excellence for Alzheimer's Disease Research and Care, School of Medical and Health Sciences, Edith Cowan University, Joondalup, WA 6027, Australia.
Ajish AriyathCentre of Excellence for Alzheimer's Disease Research and Care, School of Medical and Health Sciences, Edith Cowan University, Joondalup, WA 6027, Australia.
Kevin TaddeiCentre of Excellence for Alzheimer's Disease Research and Care, School of Medical and Health Sciences, Edith Cowan University, Joondalup, WA 6027, Australia.ORCID 0000-0002-8106-7957
Ralph N MartinsCentre of Excellence for Alzheimer's Disease Research and Care, School of Medical and Health Sciences, Edith Cowan University, Joondalup, WA 6027, Australia.ORCID 0000-0002-4828-9363
Bruno P MeloniPerron Institute for Neurological and Translational Science, Nedlands, WA 6009, Australia.ORCID 0000-0003-0964-0648

Funding

Argenica Therapeutics N/APerron Institute for Neurological and Translational Science N/A
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Alzheimer’s diseaseamyloid-betacationic arginine-rich peptidesMC65 cellsprimary cortical neuronsR18DSH-SY5Y cellstau proteintau seeds

Identifiers

PMID42512037
PMCPMC13406487

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.