Evidence map›Paper›PMID 42512034›Full record

ArticleBiomedicines2026

Liver Dysfunction Explains a Substantial Proportion of Circulating cfDNA Variability in HCC: An Exploratory Study.

Ioana Manea, Speranta Maria Iacob, Razvan Iacob, Alina-Veronica Ghionescu, Andrei Sorop, Roxana Elena Saizu, Daria-Ana-Arina Gheorghe, Delia Prisecariu, Simona Olimpia Dima, Liliana Simona Gheorghe

Abstract read
In one paragraph

Article in Biomedicines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ioana ManeaDepartment of Gastroenterology and Hepatology, Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania.ORCID 0000-0002-0226-3037
Speranta Maria IacobDepartment of Gastroenterology and Hepatology, Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania.ORCID 0000-0002-7805-5920
Razvan IacobDepartment of Gastroenterology and Hepatology, Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania.ORCID 0000-0002-8545-310X
Alina-Veronica GhionescuCenter of Excellence in Translational Medicine, Fundeni Clinical Institute, 022328 Bucharest, Romania.ORCID 0009-0000-1233-3118
Andrei SoropDepartment of Gastroenterology and Hepatology, Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania.ORCID 0000-0002-2617-4629
Roxana Elena SaizuCenter for Digestive Diseases and Liver Transplant, Fundeni Clinical Institute, 022328 Bucharest, Romania.
Daria-Ana-Arina GheorgheCenter for Digestive Diseases and Liver Transplant, Fundeni Clinical Institute, 022328 Bucharest, Romania.
Delia PrisecariuCenter for Digestive Diseases and Liver Transplant, Fundeni Clinical Institute, 022328 Bucharest, Romania.
Simona Olimpia DimaDepartment of Gastroenterology and Hepatology, Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania.ORCID 0000-0001-5275-8938
Liliana Simona GheorgheDepartment of Gastroenterology and Hepatology, Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania.

Funding

European Union This research was funded by the EU NextGenerationEU instrument through the National Recovery and Resilience Plan of Romania - Pillar III-C9-I, section I5. Establishment and operationalization of Competence Centers PNRR-III-C9-2022 - I5, managed by the Min
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ALBIbiomarkerscirculating cell-free DNAcirrhosishepatocellular carcinomaliquid biopsyPALBI

Identifiers

PMID42512034
PMCPMC13407311

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.