Circulating PANX1, P2RY2, and TLR3 Profiles in Gastric Cancer: A Preliminary Molecular Study.

Husnu Cagri Genc, Cemile Zontul, Tugba Agbektas, Gonca Kabak, Ayca Tas

Abstract read

In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Husnu Cagri GencDepartment of General Surgery, Faculty of Medicine, Sivas Cumhuriyet University, Sivas 58140, Türkiye.ORCID 0000-0001-6963-2805

Cemile ZontulDepartment of Chemistry and Chemical Processing Technologies Services, Yıldızeli Vocational School, Sivas Cumhuriyet University, Sivas 58140, Türkiye.

Tugba AgbektasDepartment of Food Processing Technologies Services, Yıldızeli Vocational School, Sivas Cumhuriyet University, Sivas 58140, Türkiye.

Gonca KabakDepartment of Medical Biochemistry, Faculty of Medicine, Sivas Cumhuriyet University, Sivas 58140, Türkiye.

Ayca TasDepartment of Medical Biochemistry, Faculty of Medicine, Sivas Cumhuriyet University, Sivas 58140, Türkiye.ORCID 0000-0002-7132-1325

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastric cancer is strongly associated with chronic inflammation and dysregulated immune signaling. Molecules involved in purinergic and innate immune pathways, including Toll-like receptor 3 (TLR3), P2Y purinoceptor 2 (P2RY2), and pannexin-1 (PANX1), may contribute to gastric cancer biology; however, their combined clinical relevance remains unknown. This study included 45 patients with gastric cancer and 45 healthy controls. The gene expression levels of

Indexed as

ConnexinsNerve Tissue ProteinsStomach NeoplasmsToll-Like Receptor 3AgedBiomarkers, TumorFemaleGene Expression Regulation, NeoplasticHumansKaplan-Meier EstimateMaleMiddle AgedPrognosisROC CurveBiomarkers, TumorConnexinsNerve Tissue ProteinsPANX1 protein, humanTLR3 protein, humanToll-Like Receptor 3gastric cancerP2RY2PANX1purinergic signalingTLR3

Identifiers

PMID42511836

DOI10.3390/ijms27146494

PMCPMC13410111

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.