ArticleInternational journal of molecular sciences2026
Curtachalasins Y1-Y13, Anti-Inflammatory Cytochalasans from the Soil Fungus
Yi-Yun Yuan, Yang Xie, Xi Zhou, Liang Tu, Ying-Meng Leng, Qi-An Chen, Qing-Hui Xiao, Shao Liu, Wen-Xuan Wang, Jing Li
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In one paragraphArticle in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 · Who and what moneyAuthors and funding
10 authors.
Yi-Yun YuanDepartment of Pharmacy, National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha 410008, China.
Yang XieDepartment of Pharmacy, National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha 410008, China.
Xi ZhouXiangya School of Pharmaceutical Sciences, Central South University, Changsha 410083, China.
Liang TuXiangya School of Pharmaceutical Sciences, Central South University, Changsha 410083, China.
Ying-Meng LengXiangya School of Pharmaceutical Sciences, Central South University, Changsha 410083, China.
Qi-An ChenDepartment of Pharmacy, National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha 410008, China.
Qing-Hui XiaoDepartment of Pharmacy, National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha 410008, China.
Shao LiuDepartment of Pharmacy, National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha 410008, China.ORCID 0000-0002-0576-8698 Wen-Xuan WangXiangya School of Pharmaceutical Sciences, Central South University, Changsha 410083, China.ORCID 0000-0002-7391-2954 Jing LiDepartment of Pharmacy, National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha 410008, China.ORCID 0000-0001-8133-507X Funding
National Natural Science Foundation of China 82173713, 82304794Natural Science Foundation of Hunan Province 2024JJ8127Postgraduate Scientific Research Innovation Project of Hunan Province 2025ZZTS0913, 2026ZZTS0160, 2025ZZTS0170Project of Hunan Administration of Traditional Chinese Medicine B2023059
6 · The paper itselfAbstract
Twenty-seven cytochalasans, including thirteen previously undescribed analogs with a 5/6/6/6 tetracyclic skeleton (curtachalasins Y1-Y13), were isolated from the rice-based culture of a soil-derived fungus,
Indexed as
Anti-Inflammatory AgentsCytochalasinsXylarialesAnimalsCytokinesLipopolysaccharidesMacrophagesMiceNitric OxideRAW 264.7 CellsSoil MicrobiologyAnti-Inflammatory AgentsCytochalasinsCytokinesLipopolysaccharidesNitric Oxideanti-inflammatory activitycytochalasansstructure elucidationXylaria sp.
Identifiers
PMID42511656
PMCPMC13409777
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