Evidence map›Paper›PMID 42511616›Full record

ArticleInternational journal of molecular sciences2026

An Endemic Region of Thiamine-Responsive Megaloblastic Anemia Caused by an

Medina Gurzhikhanova, Sergei Fomenko, Nikolay Chekanov, Olga Musharova, Tatyana Salimova, Olga Goronkova, Ruslan Abasov, Elena Raykina, Rena Zinchenko, Margarita Sharova and 7 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Medina GurzhikhanovaDmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology, and Immunology, 117198 Moscow, Russia.ORCID 0000-0002-0411-9485
Sergei FomenkoBiotech Campus LLC, 117437 Moscow, Russia.
Nikolay ChekanovBiotech Campus LLC, 117437 Moscow, Russia.ORCID 0000-0003-1131-3195
Olga MusharovaBiotech Campus LLC, 117437 Moscow, Russia.
Tatyana SalimovaDmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology, and Immunology, 117198 Moscow, Russia.
Olga GoronkovaDmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology, and Immunology, 117198 Moscow, Russia.
Ruslan AbasovDmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology, and Immunology, 117198 Moscow, Russia.ORCID 0000-0001-9179-8430
Elena RaykinaDmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology, and Immunology, 117198 Moscow, Russia.
Rena ZinchenkoResearch Centre for Medical Genetics, 115522 Moscow, Russia.ORCID 0000-0003-3586-3458
Margarita SharovaResearch Centre for Medical Genetics, 115522 Moscow, Russia.ORCID 0000-0003-3148-6915
Fizaliia KhisamievaThe State Autonomous Healthcare Institution "Children's Republican Clinical Hospital of the Ministry of Health of the Republic of Tatarstan", 420064 Kazan, Russia.
Evgeny ImyanitovDepartment of Tumor Growth Biology, N.N. Petrov Institute of Oncology, 197758 Saint Petersburg, Russia.ORCID 0000-0003-4529-7891
Anna SokolenkoDepartment of Tumor Growth Biology, N.N. Petrov Institute of Oncology, 197758 Saint Petersburg, Russia.ORCID 0000-0001-6304-1609
Evgeny KlimukBiotech Campus LLC, 117437 Moscow, Russia.ORCID 0000-0001-5314-038X
Alexey MaschanDmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology, and Immunology, 117198 Moscow, Russia.
Konstantin SeverinovBiotech Campus LLC, 117437 Moscow, Russia.ORCID 0000-0001-9706-450X
Michael MaschanDmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology, and Immunology, 117198 Moscow, Russia.ORCID 0000-0003-1735-0093

Funding

Russian Science Foundation 21-75-30015
6 · The paper itself

Abstract

Thiamine-responsive megaloblastic anemia (TRMA) is a rare autosomal recessive disorder caused by biallelic loss of function variants in the

Indexed as

Anemia, MegaloblasticDiabetes MellitusDiabetes Mellitus, Type 1Founder EffectHearing Loss, SensorineuralKetoglutarate Dehydrogenase ComplexMembrane Transport ProteinsMutationThiamine DeficiencyChild, PreschoolFemaleHomozygoteHumansInfantMaleThiamineKetoglutarate Dehydrogenase ComplexMembrane Transport ProteinsSLC19A2 protein, humanThiaminefounder effectRogers syndromeSLC19A2thiamine-responsive megaloblastic anemiawhole-genome sequencing

Identifiers

PMID42511616
PMCPMC13409991

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.