Evidence map›Paper›PMID 42511535›Full record

ReviewInternational journal of molecular sciences2026

TOR Signaling as a Central Integrator of Embryogenic Reprogramming During 2,4-D-Induced Somatic Embryogenesis.

José Luis Cabrera-Ponce, Alex Ricardo Bermudez-Valle, Maria Del Rosario Cárdenas-Aquino, Andrea Maria Navarro-Vega, Braulio Uribe-Lopez, Aaron Barraza-Celis, Eliana Valencia-Lozano, Lisset Herrera-Isidron

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

José Luis Cabrera-PonceDepartamento de Ingeniería Genética, PlanTECC, Centro de Investigación y de Estudios Avanzados del IPN, Unidad Irapuato, Irapuato 36824, Guanajuato, Mexico.ORCID 0000-0002-6142-1963
Alex Ricardo Bermudez-ValleDepartamento de Biotecnologia y Bioquimica, Centro de Investigación y de Estudios Avanzados del IPN, Unidad Irapuato, Irapuato 36824, Guanajuato, Mexico.ORCID 0009-0002-1790-9539
Maria Del Rosario Cárdenas-AquinoDepartamento de Ingeniería Genética, Centro de Investigación y de Estudios Avanzados del IPN, Unidad Irapuato, Irapuato 36824, Guanajuato, Mexico.ORCID 0000-0003-2353-1384
Andrea Maria Navarro-VegaUnidad Profesional Interdisciplinaria de Ingeniería Campus Guanajuato (UPIIG), Instituto Politécnico Nacional, Av. Mineral de Valenciana 200, Puerto Interior, Silao de la Victoria 36275, Guanajuato, Mexico.ORCID 0009-0008-9605-8843
Braulio Uribe-LopezDepartamento de Biotecnologia y Bioquimica, Centro de Investigación y de Estudios Avanzados del IPN, Unidad Irapuato, Irapuato 36824, Guanajuato, Mexico.ORCID 0009-0007-4334-219X
Aaron Barraza-CelisLaboratorio Biotechnolgika, Ignacio Ramirez 3765, La Paz 23060, Baja California Sur, Mexico.ORCID 0000-0001-7827-486X
Eliana Valencia-LozanoLaboratorio de Investigación Interdisciplinaria (LII), Universidad Nacional Autónoma de México, Escuela Nacional de Estudios Superiores, Unidad León, León de los Aldama 37684, Guanajuato, Mexico.ORCID 0000-0001-5380-326X
Lisset Herrera-IsidronUnidad Profesional Interdisciplinaria de Ingeniería Campus Guanajuato (UPIIG), Instituto Politécnico Nacional, Av. Mineral de Valenciana 200, Puerto Interior, Silao de la Victoria 36275, Guanajuato, Mexico.ORCID 0000-0001-8659-4118

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

2,4-Dichlorophenoxyacetic acid (2,4-D), originally developed as a synthetic auxinic herbicide, is the most widely used chemical inducer of somatic embryogenesis (SE) in plants. Despite extensive use of 2,4-D in plant regeneration, the systems-level regulatory mechanisms connecting hormonal signaling, metabolic reprogramming, translational control, and embryogenic competence remain poorly resolved. Here, we hypothesize that TOR signaling functions as an integrative molecular hub coordinating transcriptional, metabolic, and developmental reprogramming during somatic embryogenesis induction. To investigate the molecular regulatory landscape associated with 2,4-D-induced SE, we performed a systems-level analysis integrating publicly available transcriptomic data from

Indexed as

2,4-Dichlorophenoxyacetic AcidArabidopsisArabidopsis ProteinsCellular ReprogrammingPlant Somatic Embryogenesis TechniquesSignal TransductionTOR Serine-Threonine KinasesGene Expression Regulation, PlantPhosphatidylinositol 3-KinasesProtein Interaction Maps2,4-Dichlorophenoxyacetic AcidArabidopsis ProteinsPhosphatidylinositol 3-KinasesTOR protein, ArabidopsisTOR Serine-Threonine KinasesArabidopsis thalianacarbon metabolismDNA repairmaster regulators of somatic embryogenesismolecular mechanismribosomal proteinsomatic embryogenesisTOR signaling

Identifiers

PMID42511535
PMCPMC13409849

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.