Evidence map›Paper›PMID 42511452›Full record

ArticleInternational journal of molecular sciences2026

[(Bromomethyl)phenyl]methyl-Conjugated Chalcone Derivatives as Potential Lung Cancer Inhibitors: Structure Modification, Molecular Docking, Molecular Dynamics and In Vitro Validation.

Nathaporn Cheechana, Nopawit Khamto, Kraikrit Utama, Chawanakorn Kongsak, Puracheth Rithchumpon, Padchanee Sangthong, Puttinan Meepowpan

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nathaporn CheechanaOffice of Research Administration, Chiang Mai University, Chiang Mai 50200, Thailand.
Nopawit KhamtoDepartment of Biochemistry, Faculty of Medical Science, Naresuan University, Phitsanulok 65000, Thailand.
Kraikrit UtamaOffice of Research Administration, Chiang Mai University, Chiang Mai 50200, Thailand.ORCID 0000-0002-3458-9568
Chawanakorn KongsakOffice of Research Administration, Chiang Mai University, Chiang Mai 50200, Thailand.
Puracheth RithchumponDepartment of Chemistry, Faculty of Science, Khon Kaen University, Khon Kaen 40002, Thailand.
Padchanee SangthongDepartment of Chemistry, Faculty of Science, Chiang Mai University, 239 Huay Kaew Road, Chiang Mai 50200, Thailand.ORCID 0000-0001-8399-3367
Puttinan MeepowpanDepartment of Chemistry, Faculty of Science, Chiang Mai University, 239 Huay Kaew Road, Chiang Mai 50200, Thailand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chalcones from medicinal plants are attractive starting points for anticancer lead discovery, and this study aimed to improve the anti-NSCLC potential of 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone (DMC) from

Indexed as

Antineoplastic AgentsChalconeChalconesLung NeoplasmsAcrylamidesAniline CompoundsCarcinoma, Non-Small-Cell LungCell Line, TumorCell ProliferationErbB ReceptorsHumansIndolesMolecular Docking SimulationMolecular Dynamics SimulationPyrimidinesStructure-Activity RelationshipAcrylamidesAniline CompoundsAntineoplastic AgentsChalconeChalconesErbB ReceptorsIndolesosimertinibPyrimidines2′,4′-dihydroxy-6′-methoxy-3′,5′-dimethylchalcone (DMC)anti-lung cancer[(bromomethyl)phenyl]methyl–chalconelung cancer inhibitorsmolecular dockingmolecular dynamicsmolecular reactivitystructure modification

Identifiers

PMID42511452
PMCPMC13410135

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.