Structural Characteristics and Efficacy of Polysaccharides from Fenjiu Vinasse in Alleviating DSS-Induced Ulcerative Colitis.

Huiqin Guo, Yi Chen, Jiangying Shi, Shuhua Shan, Zhuoyu Li, Nifei Wang, Xiushan Dong

Abstract read

In one paragraph

Article in Foods (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Huiqin GuoInstitute of Biotechnology, Biomedicine and Health Laboratory in Shanxi Province, The Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Shanxi University, Taiyuan 030002, China.

Yi ChenInstitute of Biotechnology, Biomedicine and Health Laboratory in Shanxi Province, The Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Shanxi University, Taiyuan 030002, China.

Jiangying ShiInstitute of Biotechnology, Biomedicine and Health Laboratory in Shanxi Province, The Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Shanxi University, Taiyuan 030002, China.

Shuhua ShanInstitute of Biotechnology, Biomedicine and Health Laboratory in Shanxi Province, The Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Shanxi University, Taiyuan 030002, China.

Zhuoyu LiInstitute of Biotechnology, Biomedicine and Health Laboratory in Shanxi Province, The Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Shanxi University, Taiyuan 030002, China.

Nifei WangInstitute of Biotechnology, Biomedicine and Health Laboratory in Shanxi Province, The Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Shanxi University, Taiyuan 030002, China.

Xiushan DongDepartment of General Surgery, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Third Hospital of Shanxi Medical University, Tongji Shanxi Hospital, Taiyuan 030032, China.

Funding

Fundamental Research Program of Shanxi Province 202403021221006National Natural Science Foundation of China U23A20526Research and Innovation Team Project for Scientific Breakthroughs at Shanxi Bethune Hospital 2024ZHANCHI06The Key Research and Development (R&D) Program of Shanxi Province 2022ZDYF121The Open Project Program of Xinghuacun College of Shanxi University XCSXU-KF-202322

6 · The paper itself

Abstract

Vinasse, a major by-product of Fenjiu liquor production, is enriched with polysaccharides. However, their structural characteristics and potential anti-inflammatory functions remain unclear. In this study, polysaccharides from Fenjiu vinasse (VPS) were extracted and fractionated into seven sub-fractions (VPS-20 to VPS-80) via sequential alcohol precipitation. The molecular weight (Mw) of the fractions gradually decreased with increasing ethanol concentration. Monosaccharide composition analysis revealed that VPS and its fractions were mainly composed of glucose, mannose, and galactose. Among them, VPS-30 exhibited the most potent anti-inflammatory activity in LPS-induced RAW 264.7 macrophages by significantly reducing NO, IL-1β, IL-6, and TNF-α production. Structural characterization by methylation analysis and NMR spectroscopy indicated that VPS-30 contained six major glycosidic linkages, including 2,3-Ara

Indexed as

Fenjiu vinasseintestinal florapolysaccharidesstructural characterizationulcerative colitis

Identifiers

PMID42511322

DOI10.3390/foods15142575

PMCPMC13408780

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.