Evidence map›Paper›PMID 42511125›Full record

ArticleAnimals : an open access journal from MDPI2026

Trivalent AMH-INH-RFRP DNA Vaccine Enhances Estrus and Ovulation Rates in Buffaloes.

Chao Chen, Xinxin Zhang, Pei Nie, Xiaokang Lv, Yan Liang, Jinling Hua, Aixin Liang, Liguo Yang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Animals : an open access journal from MDPI, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Chao ChenCollege of Animal Science, Anhui Science and Technology University, Chuzhou 233100, China.
Xinxin ZhangAnhui Province Key Laboratory of Embryo Development and Reproductive Regulation, School of Biological and Food Engineering, Fuyang Normal University, Fuyang 236037, China.
Pei NieHunan Institute of Animal and Veterinary Science, Changsha 410125, China.
Xiaokang LvCollege of Animal Science, Anhui Science and Technology University, Chuzhou 233100, China.
Yan LiangCollege of Animal Science, Anhui Science and Technology University, Chuzhou 233100, China.ORCID 0000-0001-9747-4357
Jinling HuaCollege of Animal Science, Anhui Science and Technology University, Chuzhou 233100, China.
Aixin LiangKey Laboratory of Agricultural Animal Genetics, Breeding and Reproduction of Ministry of Education, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan 430070, China.
Liguo YangKey Laboratory of Agricultural Animal Genetics, Breeding and Reproduction of Ministry of Education, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan 430070, China.ORCID 0000-0003-1389-4640

Funding

Anhui Science and Technology University DKYJ202405National Natural Science Foundation of China 2024YFD1301301
6 · The paper itself

Abstract

backgroundBuffaloes have a significant share in the agricultural economies of many developing countries; however, the industry is not well-established because of the low reproductive efficiency of buffaloes. In this study, we designed a novel strategy to enhance buffalo reproductive efficiency and examined the significance of intramuscular AMH-INH-RFRP DNA vaccine immunization on reproductive performance.

methodsAllocated into four groups (

resultsFollowing primary immunization, antibody titers against AMH, INH, and RFRP were significantly higher in the T3 group than in the T1 group (

conclusionsIn total, intramuscular immunization with the AMH-INH-RFRP DNA vaccine, particularly at the highest dose, enhances reproductive performance in buffaloes by stimulating E

Indexed as

AMH-INH-RFRPbuffalodominant folliclereproductiontrivalent DNA vaccine

Identifiers

PMID42511125
PMCPMC13405661

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.