Evidence map›Paper›PMID 42511065›Full record

ArticleAnimals : an open access journal from MDPI2026

DNase Promotes the Release of Sperm Trapped by NETs and Induces Important Changes in Donkey Sperm Motility Patterns.

Sandra Llorens, Sebastià Company, Luisina Chapero, Iván Yánez-Ortiz, Augusto Carluccio, Ippolito De Amicis, Jaime Catalán, Jordi Miró

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sandra LlorensEquine Reproduction Service, Department of Animal Medicine and Surgery, Faculty of Veterinary Sciences, Autonomous University of Barcelona, ES-08193 Cerdanyola del Vallès, Spain.ORCID 0009-0009-6146-243X
Sebastià CompanyEquine Reproduction Service, Department of Animal Medicine and Surgery, Faculty of Veterinary Sciences, Autonomous University of Barcelona, ES-08193 Cerdanyola del Vallès, Spain.ORCID 0009-0009-8589-6523
Luisina ChaperoConsejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Centro Científico Tecnológico (CCT) Patagonia Confluencia, Neuquén 8300, Argentina.
Iván Yánez-OrtizSchool of Veterinary Medicine, Faculty of Medical, Health and Life Sciences, International University of Ecuador, Quito 170411, Ecuador.ORCID 0000-0002-3613-2481
Augusto CarluccioDepartment of Veterinary Medicine, University of Teramo, Località Piano d'Accio, IT-64100 Teramo, Italy.ORCID 0000-0002-2283-6146
Ippolito De AmicisDepartment of Veterinary Medicine, University of Teramo, Località Piano d'Accio, IT-64100 Teramo, Italy.ORCID 0000-0002-2819-4455
Jaime CatalánBiotechnology of Animal and Human Reproduction (TechnoSperm), Institute of Food and Agricultural Technology, University of Girona, ES-17003 Girona, Spain.ORCID 0000-0002-0878-7819
Jordi MiróEquine Reproduction Service, Department of Animal Medicine and Surgery, Faculty of Veterinary Sciences, Autonomous University of Barcelona, ES-08193 Cerdanyola del Vallès, Spain.ORCID 0000-0002-1085-0039

Funding

Ministry of Science and Information MCIN/AEI/10.13039/501100011033
6 · The paper itself

Abstract

A deeper understanding of the donkey's reproductive strategy is essential to improve reproductive efficiency in this species. In the jenny's uterus, sperm selection relies on the post-insemination endometrial reaction, characterized by the influx of polymorphonuclear neutrophils (PMNs), which form extracellular traps (NETs) that capture spermatozoa. Of these, some are liberated through the action of a deoxyribonuclease (DNase) present in the seminal plasma. This study aimed to develop an in vitro model to evaluate the effects of NETs and DNase action on donkey sperm viability and motility. For this purpose, donkey ejaculates were collected, PMNs were isolated from the jenny's blood and free spermatozoa were selected using a Silica gel filtration (EquiPure

Indexed as

deoxyribonuclease (DNase)donkeyneutrophil extracellular traps (NETs)polymorphonuclear neutrophils (PMNs)sperm

Identifiers

PMID42511065
PMCPMC13405748

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.