Evidence map›Paper›PMID 42510835›Full record

ArticleGenes2026

The Role of the

Karel Fusek, Petr Jansa, Jiri Forejt

Abstract read
In one paragraph

Article in Genes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Karel FusekDepartment of Cell Biology, Faculty of Science, Charles University, 128 00 Prague, Czech Republic.ORCID 0000-0003-3383-8793
Petr JansaLaboratory of Mouse Molecular Genetics, Institute of Molecular Genetics, Czech Academy of Sciences, 142 20 Prague, Czech Republic.
Jiri ForejtLaboratory of Mouse Molecular Genetics, Institute of Molecular Genetics, Czech Academy of Sciences, 142 20 Prague, Czech Republic.

Funding

Charles University 275023Czech Science Foundation 22-29928S
6 · The paper itself

Abstract

BACKGROUND/

objectivesHybrid sterility arises when two fully fertile populations produce sterile offspring, representing a key postzygotic barrier to gene flow between emerging species. In the sterile hybrid males of

methodsTo test this hypothesis, we generated an

resultsLoss of MSH2 did not restore fertility in F1 hybrids. Testes weight remained low, and no mature spermatozoa were detected. In contrast, a modest partial rescue was observed in backcross males carrying the critical

conclusionsWe examined the role of the

Indexed as

DNA Mismatch RepairHistone-Lysine N-MethyltransferaseInfertility, MaleMutS Homolog 2 ProteinAnimalsMaleMiceMice, Inbred C57BLMice, KnockoutSpermatogenesisSpermatozoaHistone-Lysine N-MethyltransferaseMsh2 protein, mouseMutS Homolog 2 Proteinprdm9 protein, mouseanti-recombinationDobzhansky–Muller incompatibilityhybrid male sterilitymeiosisMir465mismatch repairMsh2Mus musculuspachytene arrestPrdm9

Identifiers

PMID42510835
PMCPMC13409646

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.