ArticleGenes2026
Integrated Transcriptome and Metabolome Analysis Elucidates the Regulatory Networks of Salt Stress Response During Cotton Seed Germination.
Article in Genes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
1 citing paper in PubMed.
- Cotton Seed Germination Under the Main Abiotic Stress: Physiological Mechanisms, Molecular Responses, and Agronomic Strategies.Plants (Basel, Switzerland) · 2026Review
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
BACKGROUND/
objectivesSoil salinization constitutes a critical threat to global agriculture, with cotton (
methodsTo investigate the molecular basis of salt tolerance in cotton seed germination, we performed integrated transcriptomic and metabolomic profiling of
resultsTranscriptomics revealed stage-specific differentially expressed genes, with predominant downregulation and enrichment in catalytic/transporter activities. Metabolomics showed distinct reprogramming, with 210 shared differentially accumulated metabolites enriched in lipids, organic acids, terpenoids, and phenolic acids. KEGG analysis highlighted time-dependent pathway shifts: sucrose metabolism and MAPK signaling at 24 h, photosynthesis at 48 h, and cuticular lipid biosynthesis at 72 h. Weighted Gene Co-expression Network Analysis (WGCNA) identified stage-associated modules and hub genes (
conclusionOur study reveals dynamic molecular reprogramming underpinning stage-specific salt adaptation in germinating cotton seeds. These identified DEGs, DAMs, and hub genes represent promising candidate targets for molecular breeding and offer a crucial genetic basis for improving salt tolerance in cotton.
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