Evidence map›Paper›PMID 42510736›Full record

ArticleBiology2026

From Codons to Protein Structure: Evolutionary Constraints of Mitochondrial Proteins in Corvides.

Yingying Xiao, Mengsa Zhang, Mengtian Xi, Shiyun Han, Jianke Yang, Hui Peng, Wen Ge, Chenwei Dai, Lu Yang, Xianzhao Kan

Abstract read
In one paragraph

Article in Biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yingying XiaoAnhui Provincial Key Laboratory of the Conservation and Exploitation of Biological Resources, College of Life Sciences, Anhui Normal University, Wuhu 241000, China.ORCID 0009-0008-9279-7489
Mengsa ZhangAnhui Provincial Key Laboratory of the Conservation and Exploitation of Biological Resources, College of Life Sciences, Anhui Normal University, Wuhu 241000, China.ORCID 0009-0003-0166-8360
Mengtian XiAnhui Provincial Key Laboratory of the Conservation and Exploitation of Biological Resources, College of Life Sciences, Anhui Normal University, Wuhu 241000, China.
Shiyun HanAnhui Provincial Key Laboratory of the Conservation and Exploitation of Biological Resources, College of Life Sciences, Anhui Normal University, Wuhu 241000, China.ORCID 0000-0001-6834-502X
Jianke YangAnhui Provincial Key Laboratory of the Conservation and Exploitation of Biological Resources, College of Life Sciences, Anhui Normal University, Wuhu 241000, China.ORCID 0000-0002-1373-0382
Hui PengAnhui Provincial Key Laboratory of the Conservation and Exploitation of Biological Resources, College of Life Sciences, Anhui Normal University, Wuhu 241000, China.ORCID 0000-0002-4650-7910
Wen GeAnhui Provincial Key Laboratory of the Conservation and Exploitation of Biological Resources, College of Life Sciences, Anhui Normal University, Wuhu 241000, China.ORCID 0009-0005-4317-1760
Chenwei DaiAnhui Academy of Medical Sciences, Anhui Institute of Medicine, Hefei 230061, China.ORCID 0000-0002-9537-6312
Lu YangAnhui Provincial Key Laboratory of the Conservation and Exploitation of Biological Resources, College of Life Sciences, Anhui Normal University, Wuhu 241000, China.ORCID 0000-0003-0874-8841
Xianzhao KanAnhui Provincial Key Laboratory of the Conservation and Exploitation of Biological Resources, College of Life Sciences, Anhui Normal University, Wuhu 241000, China.ORCID 0000-0002-9225-407X

Funding

the 2024 Annual Provincial Quality Engineering Project of New Era Talent Cultivation (Graduate Education) 2024xscx035the Anhui Provincial Rural Revitalization Collaborative Technical Service Center, China KF202402the Department of Education of Anhui Province (Key Project on Natural Science) 2024AH052014Wuhu Institute of Technology (Major Project on Science Research) wzyzrzd202103
6 · The paper itself

Abstract

Mitochondrial codon usage and selective pressures drive adaptive evolution and translation efficiency. This study provides insights into the evolutionary constraints shaping 13 core mitochondrial proteins in Corvides, based on 117 species, including 51 newly assembled genomes. We present evidence linking codon-level sequence architecture, protein structure, and selective pressures. These protein-coding genes (PCGs) are under strong purifying selection, with dN/dS ratios ranging from 0.00779 (

Indexed as

codon aversionCorvidesfunctional constraintsmitochondrial proteinsprotein structurepurifying selection

Identifiers

PMID42510736
PMCPMC13404721

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.