Evidence map›Paper›PMID 42510697›Full record

ArticleBiology2026

Integrative Bioinformatics Prioritizes the

Pengcheng You, Anye Chen, Qiancheng Feng, Junhong Hou, Jiacheng Zheng, Hao Chen

Abstract read
In one paragraph

Article in Biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Pengcheng YouSDU-ANU Joint Science College, Shandong University, No. 180 West Wenhua Road, Weihai 264209, China.
Anye ChenSDU-ANU Joint Science College, Shandong University, No. 180 West Wenhua Road, Weihai 264209, China.
Qiancheng FengSDU-ANU Joint Science College, Shandong University, No. 180 West Wenhua Road, Weihai 264209, China.
Junhong HouMarine College, Shandong University, No. 180 West Wenhua Road, Weihai 264209, China.
Jiacheng ZhengMarine College, Shandong University, No. 180 West Wenhua Road, Weihai 264209, China.ORCID 0009-0003-1318-7986
Hao ChenMarine College, Shandong University, No. 180 West Wenhua Road, Weihai 264209, China.ORCID 0000-0001-6146-6726

Funding

foundation of Key Laboratory of Synthetic and Biological Colloids, Ministry of Education, Jiangnan University No. 1042050205243170/006National Natural Science Foundation of China NO. 32102129Shandong Provincial Natural Science Foundation No. ZR2025MS391Weihai Key Laboratory of Medical Conditioning Functional Food Processing Technology WHYY2024000Yunnan Province-City Integration Project 202302AN360002
6 · The paper itself

Abstract

Hyperuricemia (HUA) is a common immunometabolic disorder associated with gout, renal dysfunction, and systemic inflammation, yet the molecular targets through which non-starch polysaccharides (NSPs) may modulate HUA-related inflammation remain unclear. Here, we applied an integrative bioinformatics and computational workflow combining public transcriptomic datasets, curated NSP-related targets, protein-protein interaction analysis, enrichment analysis, single-cell RNA sequencing, and Mendelian randomization. We further included GutMGene-based orthogonal support analysis, guided docking, structural dynamics analysis, exploratory ADMET profiling, and in silico

Indexed as

alginatebioinformaticsfucoidanhyperuricemiaToll-like receptor 4

Identifiers

PMID42510697
PMCPMC13406026

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.