Evidence map›Paper›PMID 42510622›Full record

ArticleAntioxidants (Basel, Switzerland)2026

Wogonin Suppresses Non-Small Cell Lung Cancer Growth in Association with Oxidative Stress, c-Myc/GPX4 Downregulation and Ferroptosis-Related Responses.

Hairong Xiang, Haoshu Liu, Ruyu Jiang, Xiaomeng Tang, Linfeng Zhao, Dawei Zeng, Yue Zhang, Jiazhen Xie, Liangqin Shi, Lan Yang

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hairong XiangCollege of Basic Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.ORCID 0009-0007-5753-941X
Haoshu LiuCollege of Basic Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Ruyu JiangCollege of Basic Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.ORCID 0009-0004-8236-7048
Xiaomeng TangSchool of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Linfeng ZhaoCollege of Basic Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Dawei ZengCollege of Basic Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Yue ZhangCollege of Basic Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Jiazhen XieCollege of Basic Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Liangqin ShiCollege of Basic Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Lan YangCollege of Basic Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.

Funding

Sichuan Provincial Academy of Natural Resource Sciences 2024NSFSC0705
6 · The paper itself

Abstract

Reactive oxygen species (ROS)-regulated antioxidant defense is closely linked to non-small cell lung cancer (NSCLC) progression and therapy resistance. Wogonin (WGN), a flavonoid from

Indexed as

antioxidant defensec-Myc/GPX4ferroptosismitochondrial apoptosisnon-small cell lung canceroxidative stressreactive oxygen speciesWogonin

Identifiers

PMID42510622
PMCPMC13403425

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.