Evidence map›Paper›PMID 42510559›Full record

ArticleAntioxidants (Basel, Switzerland)2026

The Ameliorative Effects of Carnosine on the In Vitro Developmental Competence of Bovine Oocytes.

Xuan Leng, Bo-Jing Liu, Ren An, Si-Ying Chen, Kang Li, Dong Wang, Yun-Wei Pang

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xuan LengInstitute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
Bo-Jing LiuInstitute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
Ren AnInstitute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
Si-Ying ChenInstitute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
Kang LiInstitute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
Dong WangInstitute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
Yun-Wei PangInstitute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China.ORCID 0000-0002-7312-179X

Funding

the Joint Research Program of Beef Cattle Breeds of Anhui Province [2021]1146the National Key Research and Development Program of China 2023YFD1300603
6 · The paper itself

Abstract

Carnosine is a naturally occurring endogenous dipeptide with great potential to improve reproductive function and fertility. In this study, supplementation of 1 μg/mL carnosine during in vitro maturation (IVM) significantly enhanced the developmental competence and quality of the resulting bovine embryos. Carnosine treatment effectively elevated mitochondrial membrane potential, mitochondrial activity, and ATP content in oocytes. Moreover, it strengthened the antioxidant and anti-apoptotic capacities of oocytes, as evidenced by reduced intracellular reactive oxygen species (ROS) levels, lowered DNA damage and an early apoptosis rate, alongside increased glutathione (GSH) content, an elevated

Indexed as

bovinecarnosineembryomelatoninoocyteoxidative stress

Identifiers

PMID42510559
PMCPMC13404451

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.