Evidence map›Paper›PMID 42510557›Full record

ArticleAntioxidants (Basel, Switzerland)2026

Green Ultrasound-Assisted Extraction of Onion Polyphenols Using a Choline Chloride-Urea Deep Eutectic Solvent: Extraction Efficiency, Solvent Selectivity, and Antioxidant Assay Compatibility.

Mirjana S Jankulovska, Raquel Sánchez-Romero, Gabriela Guillena, José Luis Todolí-Torró

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mirjana S JankulovskaFaculty of Agricultural Sciences and Food-Skopje, Ss. Cyril and Methodius University in Skopje, P.O. Box 297, 1000 Skopje, North Macedonia.ORCID 0000-0002-3581-558X
Raquel Sánchez-RomeroDepartment of Analytical Chemistry, Nutrition and Food Sciences, University of Alicante, P.O. Box 99, 03080 Alicante, Spain.ORCID 0000-0003-0283-6103
Gabriela GuillenaDepartment of Organic Chemistry, University of Alicante, P.O. Box 99, 03080 Alicante, Spain.ORCID 0000-0001-5915-351X
José Luis Todolí-TorróDepartment of Analytical Chemistry, Nutrition and Food Sciences, University of Alicante, P.O. Box 99, 03080 Alicante, Spain.ORCID 0000-0002-9151-7050

Funding

Spanish State Research Agency (AEI) from the Ministry of Science, Innovation, and Universities PID2021-127566NB-I00
6 · The paper itself

Abstract

Deep eutectic solvents (DES) emerge as sustainable alternatives for antioxidant polyphenol extraction; however, their analytical performance and compatibility with antioxidant assays remain insufficiently characterized. A choline chloride-urea-water DES (1:2:4) was compared with 70% ethanol for extracting polyphenols from onion bulbs and peels from cultivars grown in Spain and North Macedonia. Extraction conditions were selected through a comparative evaluation of vortex- and ultrasound-assisted extraction and benchmarked against conventional ethanolic stirring (2 h). Two-way ANOVA identified solvent composition as the main determinant of total phenolic content (F(1,20) = 1526.28,

Indexed as

antioxidant activitydeep eutectic solvents (DES)Folin-Ciocâlteu assayonionpolyphenolsUHPLC-MS/MSultrasound-assisted extractionvortex-assisted extraction

Identifiers

PMID42510557
PMCPMC13405354

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.