Stress as a Common Integrative Measure Between Biology and Engineering in Bone Healing and Remodeling.

Nenad Šešić, Marijo Bekić, Maro Jelić, Miho Klaić, Antun Bekić, Cecilija Rotim, Petra Bagavac

Abstract read

In one paragraph

Article in Bioengineering (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nenad ŠešićDubrovnik County Hospital, 20000 Dubrovnik, Croatia.

Marijo BekićDubrovnik County Hospital, 20000 Dubrovnik, Croatia.ORCID 0000-0003-1754-6299

Maro JelićMaritime Department, University of Dubrovnik, 20000 Dubrovnik, Croatia.

Miho KlaićMaritime Department, University of Dubrovnik, 20000 Dubrovnik, Croatia.

Antun BekićSchool of Medicine, Catholic University of Croatia, 10000 Zagreb, Croatia.ORCID 0009-0002-7879-1618

Cecilija RotimFaculty of Dental Medicine and Health, University of Osijek, 31000 Osijek, Croatia.

Petra BagavacFaculty of Electrical Engineering, Mechanical Engineering and Naval Architecture, University of Split, 21000 Split, Croatia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study proposes mechanical stress as a common integrative parameter that connects biological bone adaptation with engineering mechanics. In engineering, stress is defined as the internal reactive force per unit area within a loaded body; in clinical practice, its biological consequences can be observed on radiographs, CT, and MRI as callus formation, hypertrophy, or oedema, and perceived by the patient as localised pain. Three-dimensional geometry models were constructed in Autodesk Fusion and Inventor, and stress distributions were visualised using Abaqus finite element analysis. Representative clinical cases (

Indexed as

biomechanical adaptationbone healingbone remodelingcallus formationfinite element method (FEM)non-unionstressstress distribution

Identifiers

PMID42510424

DOI10.3390/bioengineering13070758

PMCPMC13403804

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LicenceCC BY

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.