Evidence map›Paper›PMID 42510096›Full record

ReviewDiagnostics (Basel, Switzerland)2026

Cardiovascular Magnetic Resonance Elastography: Current Evidence, Challenges, and Future Perspectives.

Alexander Wollandt, Leon D Gruenewald, Christian Booz, Jennifer Gotta, Teodora Biciusca, Simon Bernatz, Philipp Reschke, Simon S Martin, Tatjana Gruber-Rouh, Katrin Eichler and 15 more

Abstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Alexander WollandtClinic for Radiology and Nuclear Medicine, University Hospital, Goethe University Frankfurt, 60590 Frankfurt am Main, Germany.
Leon D GruenewaldClinic for Radiology and Nuclear Medicine, University Hospital, Goethe University Frankfurt, 60590 Frankfurt am Main, Germany.ORCID 0000-0001-7959-5008
Christian BoozClinic for Radiology and Nuclear Medicine, University Hospital, Goethe University Frankfurt, 60590 Frankfurt am Main, Germany.
Jennifer GottaClinic for Radiology and Nuclear Medicine, University Hospital, Goethe University Frankfurt, 60590 Frankfurt am Main, Germany.ORCID 0000-0002-0524-6574
Teodora BiciuscaClinic for Radiology and Nuclear Medicine, University Hospital, Goethe University Frankfurt, 60590 Frankfurt am Main, Germany.
Simon BernatzClinic for Radiology and Nuclear Medicine, University Hospital, Goethe University Frankfurt, 60590 Frankfurt am Main, Germany.
Philipp ReschkeClinic for Radiology and Nuclear Medicine, University Hospital, Goethe University Frankfurt, 60590 Frankfurt am Main, Germany.
Simon S MartinClinic for Radiology and Nuclear Medicine, University Hospital, Goethe University Frankfurt, 60590 Frankfurt am Main, Germany.ORCID 0000-0003-3347-4520
Tatjana Gruber-RouhClinic for Radiology and Nuclear Medicine, University Hospital, Goethe University Frankfurt, 60590 Frankfurt am Main, Germany.
Katrin EichlerClinic for Radiology and Nuclear Medicine, University Hospital, Goethe University Frankfurt, 60590 Frankfurt am Main, Germany.
Iris BurckClinic for Radiology and Nuclear Medicine, University Hospital, Goethe University Frankfurt, 60590 Frankfurt am Main, Germany.
Scherwin MahmoudiClinic for Radiology and Nuclear Medicine, University Hospital, Goethe University Frankfurt, 60590 Frankfurt am Main, Germany.
Mohamed AlrahmounClinic for Radiology and Nuclear Medicine, University Hospital, Goethe University Frankfurt, 60590 Frankfurt am Main, Germany.
Tommaso D'AngeloClinic for Radiology and Nuclear Medicine, University Hospital, Goethe University Frankfurt, 60590 Frankfurt am Main, Germany.ORCID 0000-0003-0004-6378
Thomas J VoglClinic for Radiology and Nuclear Medicine, University Hospital, Goethe University Frankfurt, 60590 Frankfurt am Main, Germany.ORCID 0000-0001-5218-1075
Sebastian HaberkornDepartment of Cardiology, University Hospital Frankfurt, 60590 Frankfurt am Main, Germany.ORCID 0000-0003-3100-2167
Marco OchsDepartment of Cardiology, University Hospital Frankfurt, 60590 Frankfurt am Main, Germany.
Hatim KernissDepartment of Cardiology, University Hospital Frankfurt, 60590 Frankfurt am Main, Germany.ORCID 0009-0008-6430-0252
David M LeistnerDepartment of Cardiology, University Hospital Frankfurt, 60590 Frankfurt am Main, Germany.
Omar DarwishSchool of Biomedical Engineering and Imaging Sciences, King's College London, London SE1 7EH, UK.
Radhouene NejiSchool of Biomedical Engineering and Imaging Sciences, King's College London, London SE1 7EH, UK.ORCID 0000-0002-6543-4390
Ralph SinkusSchool of Biomedical Engineering and Imaging Sciences, King's College London, London SE1 7EH, UK.
Maria Johanna Gobertina Tetuanui VehreschildDepartment of Internal Medicine, Infectious Diseases, University Hospital, Goethe University Frankfurt, 60590 Frankfurt am Main, Germany.
Ralph StreckerEMEA Scientific Partnerships, Siemens Healthineers AG, 91052 Erlangen, Germany.
Vitali KochClinic for Radiology and Nuclear Medicine, University Hospital, Goethe University Frankfurt, 60590 Frankfurt am Main, Germany.ORCID 0000-0001-6915-5906

Funding

Federal Ministry of Research, Technology and Space 01EO2102National Agency for Research ANR‑21‑RHUS‑0012
6 · The paper itself

Abstract

Myocardial and aortic stiffness are increasingly recognized as clinically relevant biomarkers for cardiovascular disease, yet their noninvasive quantification remains challenging. Magnetic resonance elastography (MRE) has emerged as a promising technique for the spatial mapping of tissue biomechanics by visualizing and analyzing propagating shear waves. This narrative review summarizes the current state of cardiovascular MRE, spanning technical developments in wave generation (acoustic, electromagnetic, gravitational, and transducer-free approaches), pulse sequence design (echo-planar imaging, gradient-recalled echo, spiral, and free-breathing three-dimensional acquisitions), and inversion algorithms (local frequency estimation, direct inversion, finite element methods, and multifrequency elastography). We present evidence from phantom validation, animal models (myocardial infarction, hypertension, right ventricular hypertrophy), and human studies encompassing cardiac amyloidosis, hypertrophic cardiomyopathy, diastolic dysfunction, and abdominal aortic aneurysm. Additionally, we discuss current challenges, including waveguide effects, standardization needs, and clinical translation barriers, and highlight emerging solutions through artificial intelligence, multifrequency methods, and transducer-free cardiac MRE.

Indexed as

aortic elasticitycardiac elastographycardiovascular diseasemagnetic resonance elastographymyocardial stiffness

Identifiers

PMID42510096
PMCPMC13409057

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.