ArticleChildren (Basel, Switzerland)2026
Acute Kidney Injury in Critically Ill Children: A Retrospective Single-Center Study.
Article in Children (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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3 authors.
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Abstract
BACKGROUND AND
objectiveAcute kidney injury (AKI) is an important contributor to morbidity and mortality in critically ill children. This study aimed to determine the incidence, clinical characteristics, and outcomes of AKI in a tertiary pediatric intensive care unit (PICU).
methodsWe conducted a retrospective observational cohort study at King Abdulaziz University Hospital, Jeddah, Saudi Arabia, from January 2018 to December 2022. Children aged 29 days to 14 years who were admitted to the PICU for ≥48 h were included. AKI was defined and staged according to the 2012 KDIGO criteria. Neonates, patients with chronic kidney disease, elective or post-operative admissions, and patients with do-not-resuscitate orders were excluded.
resultsOf 1200 eligible admissions, 162 (13.5%) developed AKI: Stage 1, 44 (27.2%); Stage 2, 64 (39.5%); and Stage 3, 54 (33.3%). Greater AKI severity was associated with younger age, greater inotropic requirement, and longer mechanical ventilation (all
conclusionsAKI severity was associated with worse clinical outcomes. Early recognition, hemodynamic stabilization, timely nephrology involvement, and post-AKI follow-up are important components of care.
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