Evidence map›Paper›PMID 42509864›Full record

ReviewBiomolecules2026

Non-Mammalian Models for Mitochondria Research in CNS Disorders.

Dubravka Svob Strac, Vedrana Filic, Ana Filosevic Vujnovic, Ivana Vrhovac Madunic, Josip Madunic, Ana Cipak Gasparovic, Ana Havelka Mestrovic, Rozi Andretic Waldowski

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Biomolecules, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dubravka Svob StracRuđer Bošković Institute, 10000 Zagreb, Croatia.ORCID 0000-0001-6200-2405
Vedrana FilicRuđer Bošković Institute, 10000 Zagreb, Croatia.ORCID 0000-0001-6597-1607
Ana Filosevic VujnovicFaculty of Biotechnology and Drug Development, 51000 Rijeka, Croatia.
Ivana Vrhovac MadunicDivision of Toxicology, Institute for Medical Research and Occupational Health, 10000 Zagreb, Croatia.ORCID 0000-0002-4736-0885
Josip MadunicDivision of Toxicology, Institute for Medical Research and Occupational Health, 10000 Zagreb, Croatia.ORCID 0000-0003-4724-9236
Ana Cipak GasparovicRuđer Bošković Institute, 10000 Zagreb, Croatia.ORCID 0000-0003-2000-8950
Ana Havelka MestrovicDepartment of Psychology, Algebra Bernays University, 10000 Zagreb, Croatia.
Rozi Andretic WaldowskiFaculty of Biotechnology and Drug Development, 51000 Rijeka, Croatia.ORCID 0000-0003-0375-0520

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mitochondrial dysfunction is increasingly recognized as a major contributor to central nervous system (CNS) disorders, including neurodegenerative and neuropsychiatric diseases. Animal models are essential for elucidating disease mechanisms and supporting the development of new therapeutic strategies. Among these models, non-mammalian organisms offer distinct advantages, including low cost, rapid life cycles, genetic tractability, and suitability for large-scale, high-throughput studies. Organisms such as

Indexed as

Central Nervous System DiseasesMitochondriaAnimalsCaenorhabditis elegansDisease Models, AnimalDrosophila melanogasterHumansCaenorhabditis elegansCNS disordersDanio rerioDictyostelium discoideumDrosophila melanogastermitochondrianon-mammalian modelsSaccharomyces cerevisiae

Identifiers

PMID42509864
PMCPMC13406580

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.