Evidence map›Paper›PMID 42509729›Full record

ArticleBiomolecules2026

Colon Histophysiological Features and Gut Microbiome in Tolerant and Susceptible to Oxygen Deficiency Wistar Rats After the Prolonged Intermittent Hypoxic Exposure.

Maria Kirillova, Dzhuliia Dzhalilova, Natalia Zolotova, Vladimir Kirillov, Larisa Ogneva, Mikhail Kirillov, Tatiana Portnova, Natalia Berlizeva, Nikolai Fokichev, Olga Makarova

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Maria KirillovaLaboratory of Immunomorphology of Inflammation, Petrovsky National Research Center for Surgery, Moscow 117418, Russia.ORCID 0000-0002-7781-5537
Dzhuliia DzhalilovaLaboratory of Immunomorphology of Inflammation, Petrovsky National Research Center for Surgery, Moscow 117418, Russia.ORCID 0000-0002-1337-7160
Natalia ZolotovaLaboratory of Immunomorphology of Inflammation, Petrovsky National Research Center for Surgery, Moscow 117418, Russia.ORCID 0000-0002-0119-9889
Vladimir KirillovLaboratory of Molecular Genetics, National Medical Research Center for Obstetrics, Gynecology and Perinatology Named After Academician V. I. Kulakov of Ministry of Health of Russian Federation, Moscow 117997, Russia.ORCID 0000-0002-8762-1322
Larisa OgnevaDNA-Technology Ltd., Moscow 117587, Russia.ORCID 0009-0000-0547-4393
Mikhail KirillovDNA-Technology Ltd., Moscow 117587, Russia.ORCID 0009-0005-5578-4492
Tatiana PortnovaLaboratory of Immunomorphology of Inflammation, Petrovsky National Research Center for Surgery, Moscow 117418, Russia.
Natalia BerlizevaLaboratory of Immunomorphology of Inflammation, Petrovsky National Research Center for Surgery, Moscow 117418, Russia.
Nikolai FokichevLaboratory of Immunomorphology of Inflammation, Petrovsky National Research Center for Surgery, Moscow 117418, Russia.
Olga MakarovaLaboratory of Immunomorphology of Inflammation, Petrovsky National Research Center for Surgery, Moscow 117418, Russia.ORCID 0000-0001-8581-107X

Funding

Russian Science Foundation 25-25-00061
6 · The paper itself

Abstract

Systemic hypoxia influences the state of the intestinal epithelial barrier and the microbiome; however, the role of the initial tolerance of the organism to oxygen deficiency in the development of these changes remains poorly studied. The aim of the study was to evaluate the colon histophysiological features and the gut microbiome in rats that were tolerant and susceptible to hypoxia under intermittent hypoxic exposure of varying severity. In male Wistar rats, tolerance to oxygen deficiency was determined according to the

Indexed as

ColonGastrointestinal MicrobiomeHypoxiaOxygenAnimalsBasic Helix-Loop-Helix ProteinsEndothelial PAS Domain-Containing Protein 1Hypoxia-Inducible Factor 1, alpha SubunitIntestinal MucosaMaleRatsRats, WistarBasic Helix-Loop-Helix ProteinsEndothelial PAS Domain-Containing Protein 1Hypoxia-Inducible Factor 1, alpha SubunitOxygenguthistophysiologyhypoxic loadmicrobiometolerance to hypoxia

Identifiers

PMID42509729
PMCPMC13406623

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.