Evidence map›Paper›PMID 42509622›Full record

Trial reportBJU international2026

A stent-plus-irrigation protocol after adolescent hypospadias repair: a multicentre randomised controlled trial.

Zihan Ye, Hongsong Chen, Qiang Zhang, Xingguo Luo, Zhicheng Zhang, Guanghui Wei, Li Zeng, Ning Li, Gaofeng Zhang, Wei Liu and 1 more

Abstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in BJU international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Zihan YeDepartment of Urology, Children's Hospital of Chongqing Medical University, Chongqing, China.
Hongsong ChenDepartment of Urology, Children's Hospital of Chongqing Medical University, Chongqing, China.
Qiang ZhangDepartment of Urology, Children's Hospital of Chongqing Medical University, Chongqing, China.ORCID 0000-0003-4328-7630
Xingguo LuoDepartment of Urology, Children's Hospital of Chongqing Medical University, Chongqing, China.
Zhicheng ZhangDepartment of Urology, Children's Hospital of Chongqing Medical University, Chongqing, China.
Guanghui WeiDepartment of Urology, Children's Hospital of Chongqing Medical University, Chongqing, China.
Li ZengDepartment of Pediatric Surgery, West China Hospital, Sichuan University, Chengdu, China.
Ning LiDepartment of Pediatric Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Gaofeng ZhangDepartment of Urology, Xi'an Children's Hospital, Xi'an Jiaotong University Affiliated Children's Hospital, Xi'an, Shaanxi, China.
Wei LiuDepartment of Pediatric Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Shandong, China.
Xing LiuDepartment of Urology, Children's Hospital of Chongqing Medical University, Chongqing, China.ORCID 0000-0002-9249-1366

Funding

Chongqing Science and Technology Bureau, project "Clinical Intervention for Structural Abnormalities of the Pediatric Urogenital System" CSTB2025TIAD-LYKJXZJSYYX0005National Natural Science Foundation of China 82501925
6 · The paper itself

Abstract

objectivesTo evaluate whether a stent-plus-irrigation protocol reduces complication rates following hypospadias repair in adolescents compared with catheter drainage alone. PATIENTS AND

methodsIn this multicentre randomised controlled trial, adolescents (Tanner Stage II-V) undergoing hypospadias repair were randomly assigned to either a stent-plus-irrigation group or a catheter-drainage group. The catheter-drainage group received standard urethral catheter drainage alone, whereas the stent-plus-irrigation group received an additional small-calibre urethral stent positioned within the reconstructed urethra and twice-daily saline irrigation. The primary outcome was the overall postoperative complication rate; secondary outcomes included urinary function and cosmetic outcomes.

resultsA total of 172 adolescents were assessed for eligibility, with 150 participants (75 in the stent-plus-irrigation group and 75 in the catheter-drainage group) included in the final analysis. Compared with the catheter-drainage group, the stent-plus-irrigation group demonstrated a significantly lower overall complication rate (risk ratio [RR] 0.33, 95% confidence interval [CI] 0.20-0.56; P < 0.001), urethral fistula rate (RR 0.27, 95% CI 0.14-0.51; P < 0.001), and surgical site infection (SSI) rate (RR 0.43, 95% CI 0.21-0.87; P = 0.020).

conclusionsA postoperative stent-plus-irrigation protocol was associated with lower rates of postoperative complications, particularly urethral fistula and SSI, compared with catheter drainage alone after adolescent hypospadias repair. Because the intervention included both an additional urethral stent and saline irrigation, the independent contribution of irrigation cannot be determined in this two-arm trial.

Indexed as

HypospadiasPostoperative ComplicationsStentsTherapeutic IrrigationAdolescentChildDrainageHumansMaleTreatment OutcomeUrethraUrinary Catheterizationcomplicationshypospadiasmulticentrerandomised controlled trialstent‐plus‐irrigation protocol

Identifiers

PMID42509622
PMCPMC13550781

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.