Evidence map›Paper›PMID 42509595›Full record

ArticleNeurogastroenterology and motility2026

Methane Trajectory Phenotypes on Glucose Breath Testing Are Associated With Slow Colonic Transit: A Group-Based Trajectory Modeling Analysis.

Jarongkorn Sirimongkolkasem, Briana Valencia, Laren Becker, Sean Spencer, Irene Sonu, Linda Nguyen, Leila Neshatian

Abstract read
In one paragraph

Article in Neurogastroenterology and motility, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jarongkorn SirimongkolkasemDivision of Gastroenterology & Hepatology, Stanford University, Palo Alto, California, USA.ORCID https://orcid.org/0000-0002-3628-4290
Briana ValenciaDivision of Gastroenterology & Hepatology, Stanford University, Palo Alto, California, USA.ORCID https://orcid.org/0009-0005-8221-6626
Laren BeckerDivision of Gastroenterology & Hepatology, Stanford University, Palo Alto, California, USA.
Sean SpencerDivision of Gastroenterology & Hepatology, Stanford University, Palo Alto, California, USA.ORCID https://orcid.org/0000-0002-7328-5399
Irene SonuDivision of Gastroenterology & Hepatology, Stanford University, Palo Alto, California, USA.ORCID https://orcid.org/0000-0002-6346-1627
Linda NguyenDivision of Gastroenterology & Hepatology, Stanford University, Palo Alto, California, USA.
Leila NeshatianDivision of Gastroenterology & Hepatology, Stanford University, Palo Alto, California, USA.ORCID https://orcid.org/0000-0003-4153-5012

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntestinal methanogen overgrowth (IMO) is defined by a single binary threshold of CH

methodsWe retrospectively analyzed 188 adults with constipation who underwent glucose breath testing and colonic transit assessment. Group-based trajectory modeling was used to classify CH KEY

resultsSixty-nine patients (36.7%) had slow colonic transit, and 61 (32.4%) met IMO criteria. Three CH

conclusionsCH

Indexed as

ConstipationGastrointestinal TransitGlucoseMethaneAdultAgedBreath TestsFemaleHumansMaleMiddle AgedPhenotypeRetrospective StudiesGlucoseMethanebreath testingchronic constipationcolonic transitgroup‐based trajectory modelingintestinal methanogen overgrowthmethane

Identifiers

PMID42509595
PMCPMC13408215

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.