Evidence map›Paper›PMID 42509538›Full record

ReviewBMC neurology2026

The early fogging effect in cerebral infarction - a case report and review of the literature.

Luisa M Müller, Daniel Dubinski, Justus Groß, Peter Donndorf, Matthias Wittstock, Daniel Cantré, Thomas M Freiman, Jens-Christian Schewe, Florian Geßler, Gerd Klinkmann and 1 more

Abstract readCase ReportsReview
In one paragraph

Review in BMC neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Luisa M MüllerDepartment of Neurosurgery, Rostock University Medical Center, Schillingallee 35, Rostock, 18057, Germany. luisamarie.mueller@med.uni-rostock.de.ORCID http://orcid.org/0009-0009-0227-9838
Daniel DubinskiDepartment of Neurosurgery, Rostock University Medical Center, Schillingallee 35, Rostock, 18057, Germany.
Justus GroßDepartment of General and Vascular Surgery, Rostock University Medical Center, Rostock, Germany.
Peter DonndorfDepartment of General and Vascular Surgery, Rostock University Medical Center, Rostock, Germany.
Matthias WittstockDepartment of Neurology, Rostock University Medical Center, Rostock, Germany.
Daniel CantréDepartment of Radiology, Rostock University Medical Center, Rostock, Germany.
Thomas M FreimanDepartment of Neurosurgery, Rostock University Medical Center, Schillingallee 35, Rostock, 18057, Germany.
Jens-Christian ScheweDepartment of Anesthesiology, Intensive Care Medicine and Pain Therapy, Rostock University Medical Center, Rostock, Germany.
Florian GeßlerDepartment of Neurosurgery, Rostock University Medical Center, Schillingallee 35, Rostock, 18057, Germany.
Gerd Klinkmann *Department of Anesthesiology, Intensive Care Medicine and Pain Therapy, Rostock University Medical Center, Rostock, Germany.
Sae-Yeon Won *Department of Neurosurgery, Rostock University Medical Center, Schillingallee 35, Rostock, 18057, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe fogging effect is a well-known phenomenon usually seen two to three weeks post stroke, characterized by a pseudonormalization of the infarcted tissue. CASE PRESENTATION: A 62-year-old patient underwent emergent thoracic endovascular aortic repair (TEVAR) due to a Stanford Type B aortic dissection. Post-intervention dual antiplatelet therapy and systemic anticoagulation were administered. The following day, the patient developed acute neurological deficits. Cranial CT and perfusion imaging demonstrated an infarction in the left posterior inferior cerebellar artery territory, and conservative management was pursued. A follow-up CT scan 27 h later revealed an isodense area within the infarcted region consistent with the fogging effect.

conclusionOur case demonstrated this fogging effect at an unusually early timepoint. We hypothesize that systemic therapeutic anticoagulation together with dual antiplatelet therapy may have contributed to the early onset of fogging. This case highlights the limitations of non-contrast CT in stroke assessment and underscores the importance of multimodal imaging and awareness of this phenomenon.

Indexed as

Cerebral InfarctionAnticoagulantsHumansMaleMiddle AgedPlatelet Aggregation InhibitorsTomography, X-Ray ComputedAnticoagulantsPlatelet Aggregation InhibitorsCerebellar infarctionFogging effectIschemic strokeNeuroimaging artefactsStroke imaging

Identifiers

PMID42509538
PMCPMC13404108

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.