Evidence map›Paper›PMID 42509492›Full record

ArticleJournal of artificial organs : the official journal of the Japanese Society for Artificial Organs2026

Adsorption characteristics of erythropoietin in two β2-microglobulin absorption systems: a preliminary in vitro study using FILTOR

Shoichiro Hara, Masakazu Hirose, Taisuke Goto, Katsuro Imamura

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shoichiro HaraMedical Corporation Imamura Clinic, 2-2-1 Kongo Yahatanishiku, Kitakyushushi, Fukuokaken, 807-1263, Japan. s.hara.imacli@gmail.com.
Masakazu HiroseMedical Corporation Imamura Clinic, 2-2-1 Kongo Yahatanishiku, Kitakyushushi, Fukuokaken, 807-1263, Japan.
Taisuke GotoMedical Corporation Imamura Clinic, 2-2-1 Kongo Yahatanishiku, Kitakyushushi, Fukuokaken, 807-1263, Japan.
Katsuro ImamuraMedical Corporation Imamura Clinic, 2-2-1 Kongo Yahatanishiku, Kitakyushushi, Fukuokaken, 807-1263, Japan. Imamuraclinic2022@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo compare the erythropoietin adsorption characteristics of two adsorption devices, Lixelle

methodsThree recirculating perfusion studies were performed using bovine serum containing recombinant human erythropoietin (epoetin beta; EPO), darbepoetin alfa (DA), or epoetin beta pegol (C.E.R.A.). Because direct quantitative assays for DA and C.E.R.A. were unavailable, and it was difficult to obtain suitable measurement systems for these agents, they were evaluated using an erythropoietin immunoassay based on assay cross-reactivity.

resultsIn the EPO perfusion test (n = 3), the 4-h EPO removal rate was 18.7 ± 3.2% in the Lixelle

conclusionsThe FILTOR

Indexed as

Amyloidosisbeta 2-MicroglobulinErythropoietinRenal DialysisAdsorptionAnimalsCattleDarbepoetin alfaHumansRecombinant Proteinsbeta 2-MicroglobulinDarbepoetin alfaepoetin betaErythropoietinRecombinant ProteinsDarbepoetin alfaDialysis-related amyloidosisEpoetin beta pegolHypoxia-inducible factor prolyl hydroxylase

Identifiers

PMID42509492

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.