Hungry, hungry bones: electrolyte abnormalities in the presence of severe malnutrition.

Eva M Goren, Stephanie N Ferrin, Sowmya Krishnan, Amy B Middleman

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In one paragraph

Review in Hormones (Athens, Greece), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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5 · Who and what money

Authors and funding

4 authors.

Eva M GorenDepartment of Life Sciences, University of Michigan, 210 Washtenaw Ave, Ann Arbor, MI, 48109, USA. evagoren@umich.edu.ORCID http://orcid.org/0009-0008-2040-9395

Stephanie N FerrinDepartment of Pediatrics, Section of Adolescent Medicine, University of Oklahoma Health Sciences Center, 1200 Children's Avenue, Suite 12110, Oklahoma City, OK, 73104, USA.

Sowmya KrishnanDepartment of Pediatrics, University of Texas Southwestern Medical Center, Dallas, USA.

Amy B MiddlemanDivision of Academic Pediatrics and Adolescent Medicine, Department of Pediatrics, University Hospitals, 5805 Euclid Ave., Cleveland, OH, 44103, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe malnutrition in the presence of child maltreatment and other specified feeding or eating disorder (OSFED) can lead to significant effects on bones. We present a case of severe malnutrition from child maltreatment that developed into osteoporosis and persistent electrolyte abnormalities due to hungry bone syndrome (HBS). We describe a 15-year-old female with a history of medical neglect and severe malnutrition presenting to the hospital after removal from mother's home. The patient was admitted, refed, and monitored for refeeding syndrome. She had an elevated parathyroid hormone (PTH) level, vitamin D deficiency, and electrolyte derangements requiring daily management for weeks. Once obtained, a dual-energy X-ray absorptiometry (DXA) scan demonstrated a total-body-less-head (TBLH) Z score of -5.9. The learning goals of this case are for the readers to: ● Understand the pathophysiology and typical presentation of HBS. ● Understand the unique presentation of HBS in the context of malnutrition. ● Distinguish HBS from refeeding syndrome.

Indexed as

Adolescent healthAnorexia nervosaDXA scanHungry bone syndromeSevere malnutrition

Identifiers

PMID42509471

DOI10.1097/MNH.0000000000000327

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.