Evidence map›Paper›PMID 42509307›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2026

Pre-transfusion platelet counts and bleeding in very low birth weight infants.

Elizabeth F Stone, Rebecca Birch, Jeanne E Hendrickson, Erika M Edwards, Ruchika Goel, Eldad A Hod, Matthew Karafin, Oliver Karam, Naomi L C Luban, Jennifer McIntosh and 8 more

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors.

Elizabeth F StoneDepartment of Pathology & Cell Biology, Columbia University Irving Medical Center, New York, NY, USA. es2024@cumc.columbia.edu.ORCID http://orcid.org/0000-0002-4148-7957
Rebecca BirchWestat, Rockville, MD, USA.
Jeanne E HendricksonDepartment of Pathology and Laboratory Medicine, Center for Transfusion and Cellular Therapies, Emory University School of Medicine, Atlanta, GA, USA.ORCID http://orcid.org/0000-0002-7928-3132
Erika M EdwardsVermont Oxford Network, Burlington, VT, USA.
Ruchika GoelDepartment of Internal Medicine, Simmons Cancer Institute, Southern Illinois University School of Medicine, Springfield, IL, USA.
Eldad A HodDepartment of Pathology & Cell Biology, Columbia University Irving Medical Center, New York, NY, USA.ORCID http://orcid.org/0000-0002-2367-9509
Matthew KarafinDepartment of Pathology and Lab Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Oliver KaramDepartment of Pediatrics, Pediatric Critical Care Medicine, Yale School of Medicine, New Haven, CT, USA.ORCID http://orcid.org/0000-0001-6606-1736
Naomi L C LubanChildren's National Research Institute, Washington, DC, USA.
Jennifer McIntoshDepartment of Obstetrics & Gynecology, Medical College of Wisconsin, Milwaukee, WI, USA.
Gisela Marrero-RiveraDepartment of Laboratory Medicine, University of California San Franscisco, San Franscisco, USA.
Marianne E NellisDepartment of Pediatrics, Division of Critical Care Medicine, Weill Cornell Medicine, New York, NY, USA.
Jeffrey VanWormerMarshfield Clinic Research Institute, Marshfield, WI, USA.
Nalan YurtseverDepartment of Laboratory Medicine, Yale University School of Medicine, New Haven, CT, USA.ORCID http://orcid.org/0000-0001-7807-6046
Cassandra D JosephsonJohns Hopkins All Children's Hospital, Cancer and Blood Disorders Institute, St, Petersburg, FL, USA.ORCID http://orcid.org/0000-0003-2543-991X
Martha Sola-VisnerBoston Children's Hospital and Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0002-0013-598X
Ravi M PatelDepartment of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA, USA. rmpatel@emory.edu.ORCID http://orcid.org/0000-0002-7444-5550
NHLBI Recipient Epidemiology and Donor Evaluation Study-IV-P (REDS-IV-P)

Funding

(REDS-IV-P) RECIPIENT EPIDEMIOLOGY AND DONOR EVALUATION STUDY IV-DATA75N92019D00032 · NHLBI · WESTAT, INC. · PI CHAPMAN, KATHY · 2019 to 2025
$19.6M
(REDS-IV-P) RECIPIENT EPIDEMIOLOGY AND DONOR EVALUATION STUDY IV75N92019D00036 · NHLBI · YALE UNIVERSITY · PI HENDRICKSON, JEANNE E · 2019 to 2024
$6.7M
REDS-IV-P DOMESTIC HUBS PHASE 275N92019D00035 · NHLBI · VERSITI WISCONSIN, INC. · PI MAST, ALAN E · 2019 to 2024
$6.6M
REDS-IV-P DOMESTIC HUBS PHASE 275N92019D00037 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI HOD, ELDAD ARIE · 2019 to 2024
$6.6M
(REDS-IV-P) RECIPIENT EPIDEMIOLOGY AND DONOR EVALUATION STUDY IV-DOMESTIC HUBS75N92019D00034 · NHLBI · VITALANT · PI CUSTER, BRIAN · 2020 to 2024
$5.3M
NHLBI NIH HHS 75N92019D00032NHLBI NIH HHS 75N92019D00034NHLBI NIH HHS 75N92019D00035NHLBI NIH HHS 75N92019D00036NHLBI NIH HHS 75N92019D00037
6 · The paper itself

Abstract

objectivePlatelet transfusion thresholds for very low birth weight (VLBW, <1500 g) infants vary widely, and the role of bleeding on platelet transfusion thresholds is uncertain. STUDY

designThis observational birth cohort study of VLBW infants born in 7 hospitals across the US examined pre-transfusion platelet counts in infants with and without bleeding who received at least 1 platelet transfusion in the first 3 weeks of life using mixed effect linear regression models.

resultsOf the 210 transfused infants, most (76%) had bleeding; intraventricular hemorrhage (IVH) was the most common (61%) bleeding type. Pre-transfusion platelet counts were not different among infants with or without bleeding diagnoses (56.3 vs 58.5 × 10

conclusionInfants with or without bleeding diagnoses had similar pre-transfusion platelet counts; infants with severe IVH had higher pre-transfusion platelet counts.

Identifiers

PMID42509307

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.